Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Increase in the reliability of brain tumour diagnosis


A team of European researchers lead by Carles Arús, professor at the Department of Biochemistry and Molecular Biology of the Universitat Autònoma de Barcelona, have developed a system that facilitates the interpretation of magnetic resonance spectra of brain tumours and improves their diagnosis. It is a computer-based tool that visually classifies the different types of tumours. The new system has significantly improved the reliability of the diagnosis in preliminary tests with 16 patients.

There are 50 different types and grades of malignant tumours. The malignancy of each type of tumour is what determines if and what type of therapy is the best one to carry out. Radiologists use images of the brain, obtained by different exploratory techniques, to diagnose the type of tumour as well as using magnetic resonance (MR) spectra of the tumour. These spectra are curves with different patterns, which are associated with the abundance of the different chemical substances in its composition. Explorations with images obtained from MR have an average reliability for diagnosing a type of tumour of between 75 and 80%. The only alternative currently available to increase this reliability is the biopsy with the consequent risks that are involved with that type of intervention.

Carles Arús, professor at the Department of Biochemistry and Molecular Biology of the Universitat Autònoma de Barcelona, lead a team of researchers from various European institutions in carrying out the European project called, INTERPRET (International Network for Pattern Recognition of Tumours Using Magnetic Resonance). The scientists have developed a computer-based system that classifies on the screen, in a visual manner, different types of tumours according to their magnetic resonance spectra. The system is very flexible with the origin and technical characteristics of the spectra, which makes it quite useful in cases in which the MR spectra were obtained from different apparatus or from different clinics.

Thanks to this new system, radiologists, who are accustomed to making diagnoses based on images of the brain, do not have to have specific abilities in interpreting MR spectra to improve their diagnoses. This decision support tool is based on a database that includes information on 300 brain tumours. Each one was validated by following quality control protocols established over the course of the study. A point on a graph represents each case. Its position is determined by the characteristics of the MR spectrum in such a way that tumours with a similar origin appear represented on the graph in nearby positions. When a doctor receives the spectrum corresponding to a patient with a tumour of unknown origin, the computer system locates it on the graph taking into account its distinctive characteristics. In this way, the radiologist obtains visual information on the probability that the unknown tumour is either one type or another according to the area of the graph on which it is found.

The system has been successfully tested in a preliminary study on 16 patients. In that study, the combination of information that the new system offered from the images of tumours obtained from brain explorations made it possible to achieve a 92% degree of reliability in diagnoses. That means a 4% increase in the reliability obtained with the images of just that specific group of patients.

The system has been ceded for commercialisation to the SCITO S.A. company. In addition to the participation of the Department of Biochemistry and Molecular Biology of the Universitat Autònoma de Barcelona, the following groups and institutes have participated in the research carried out: l’Institut de Diagnòstic per la Imatge and the Centre Diagnòstic in Pedralbes (Barcelona), St. George’s Hospital Medical School and the University of Sussex (UK), l’INSERM/Université Joseph Fourier in Grenoble, the French company PRAXIM SARL, the Katholieke Universiteit Nijmegen (Holland) and the German company Siemens AG.

Octavi López Coronado | alfa
Further information:

More articles from Health and Medicine:

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

nachricht New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>