Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Artificial membranes can reveal biological weapons

16.01.2004


Today there is a great need for portable equipment that can quickly detect chemical and biological weapons such as nerve gases, viruses, bacteria, and toxins. In a new dissertation the Swedish researcher Inga Gustafsson shows that artificial membranes can be used for this purpose in future biosensors.



Biosensors have already proven to be useful in the detection of impurities in food and water, for example. They have also been used in industrial processes, clinical analyses, and the development of pharmaceuticals.

In her dissertation, Inga Gustafsson, Department of Chemistry, Umeå University, and FOI, the Swedish Defence Research Agency , studies artificial membranes in biosensors.


Many hazardous substances bind to receptors in cell membranes at some stage. By using artificial membranes with specific binding sites it has been shown that these membranes can be used in future biosensors for detecting hazardous substances.

Inga Gustafsson’s study has helped identify factors that can affect the construction of model membranes on solid surfaces. These have proven to be of use in studying reactions occurring on the cell membrane. With further development they can be suitable for use as sensor surfaces in biosensors.

The membranes have been characterized and tested using various techniques. The experiments could be repeated with good stability. Membrane proteins have been built into the membranes and analyzed in regard to retained activity. The proteins introduced were bacteriorhodopsin, cytochrome oxidase, acetylcholine esterase, and the nicotine-like acetylcholine receptor.

The investigation revealed that the proteins were individually distributed in the membrane and that they retained their activity. Certain proteins were active for several weeks. Various glycolipids that can act as receptors for bacteria, viruses, and toxins were also introduced in the artificial membranes. The binding of the toxin ricin to these receptors was studied. The binding of the toxin to the membrane with glycolipids varied depending on pH, charge, and length of the sugar segment of the sugar lipid.

Carina Dahlberg | alfa
Further information:
http://www.umu.se/english

More articles from Health and Medicine:

nachricht Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

Bare bones: Making bones transparent

27.04.2017 | Life Sciences

Study offers new theoretical approach to describing non-equilibrium phase transitions

27.04.2017 | Physics and Astronomy

From volcano's slope, NASA instrument looks sky high and to the future

27.04.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>