In fighting cancer, the sooner doctors can determine how a patient will respond to a particular therapy, the more effective overall treatment will be. Researchers have now shown that 18F-FDG PET scans are better than CT scans at predicting response to imatinib mesylate, a drug that has recently been found effective in treating gastrointestinal stromal tumors (GISTs).
The result is significant, as the PET scan allows doctors to determine if the therapy regimen is working very early in the treatment process, providing information that will allow physicians and patients to decide as soon as possible whether to continue treatment with imatinib mesylate or try a different therapy.
The study, which was conducted by researchers at the University of Texas M.D. Anderson Cancer Center in Houston, Texas, was published in the January 2004 edition of The Journal of Nuclear Medicine. They conducted the retrospective analysis by examining the sensitivity and predictive values of PET and CT scans taken prior to therapy and then again two months after imatinib mesylate treatment had begun. While there was no significant statistical difference between the pretreatment accuracy of the two different types of scans, PET was more effective in early assessment of the patients responses to the drug.
Kimberly A. Bennett | EurekAlert!
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Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
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Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
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A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
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