In fighting cancer, the sooner doctors can determine how a patient will respond to a particular therapy, the more effective overall treatment will be. Researchers have now shown that 18F-FDG PET scans are better than CT scans at predicting response to imatinib mesylate, a drug that has recently been found effective in treating gastrointestinal stromal tumors (GISTs).
The result is significant, as the PET scan allows doctors to determine if the therapy regimen is working very early in the treatment process, providing information that will allow physicians and patients to decide as soon as possible whether to continue treatment with imatinib mesylate or try a different therapy.
The study, which was conducted by researchers at the University of Texas M.D. Anderson Cancer Center in Houston, Texas, was published in the January 2004 edition of The Journal of Nuclear Medicine. They conducted the retrospective analysis by examining the sensitivity and predictive values of PET and CT scans taken prior to therapy and then again two months after imatinib mesylate treatment had begun. While there was no significant statistical difference between the pretreatment accuracy of the two different types of scans, PET was more effective in early assessment of the patients responses to the drug.
Kimberly A. Bennett | EurekAlert!
Fast-tracking T cell therapies with immune-mimicking biomaterials
16.01.2018 | Wyss Institute for Biologically Inspired Engineering at Harvard
Dengue takes low and slow approach to replication
12.01.2018 | Duke University
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
16.01.2018 | Materials Sciences
16.01.2018 | Materials Sciences
16.01.2018 | Power and Electrical Engineering