Studies on common bakers yeast have led to the discovery of what may be a long-sought mechanism in the life cycle of retroviruses, including the human immunodeficiency virus (HIV). Knowing the details of this step in the infection process could help pinpoint targets for new classes of drugs to fight HIV.
In the Jan. 9 issue of the journal Science, Thomas Menees and Zhi Cheng of the University of Missouri-Kansas City describe the formation of a lariat structure with the genetic material of retrovirus-like elements in bakers yeast and subsequent cutting of the lariat by a yeast enzyme. The findings reported in Science and in the December 2003 Journal of Virology are the payoff of a three-year research gamble by Menees and two postdoctoral researchers pursuing host-cell factors in retroviral infections.
In addition to filling a gap in biologists understanding of how retroviruses replicate, it may turn out that similar lariat structures occur elsewhere in healthy cells and play previously unrecognized roles in cellular processes such as gene activation.
David Hart | NSF
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MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
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Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
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