Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Nasal spray flu vaccine may help prevent influenza in healthy children

06.01.2004


An influenza virus vaccine delivered as a nasal spray, appears to be effective in protecting healthy children against certain strains of influenza, according to an article in the January issue of The Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.



Each winter, influenza causes significant illness in all age groups, according to the article. The U.S. Food and Drug Administration recently approved an influenza virus vaccine (cold-adapted trivalent influenza virus vaccine, or CAIV-T) administered in the form of a nasal spray for use in healthy children and adults aged 5 through 49 years. Previous studies have shown that the nasal spray was successful in preventing influenza A (H3N2) and B infections in children 15 months old to about 6 years old, and was effective in preventing certain strains of the influenza virus from infecting adults. However, the ability of CAIV-T to prevent natural influenza A (H1N1) infection is unknown.

Manjusha J. Gaglani, M.B.B.S., from the Scott & White Memorial Hospital and Clinic, Temple, Tex., and colleagues assessed the effectiveness of CAIV-T in healthy children during the 2000-2001 influenza A (H1N1) epidemic.


The incidence of respiratory infections that resulted in a medical visit among 3,794 healthy children aged 1.5 to 18 years who received the CAIV-T vaccine at least once in 1998, 1999 and/or 2000 was compared with the incidence among 9,325 healthy non-recipient children and adolescents in the same communities, and 16,264 in two other communities.

The researchers found, "Significant direct effectiveness of CAIV-T for prevention of [acute respiratory illness] in all age groups and in all children vaccinated in 2000 was observed during the entire influenza A and B epidemic. Direct effectiveness in all children and children aged 1.5 to 4 and 5 to 9 years during the six weeks when influenza A (H1N1) viruses predominated documented effectiveness of CAIV-T against natural influenza A (H1N1) infection for the first time," write the authors.


(Arch Pediatr Adolesc Med. 2004;158:65-73. Available post-embargo at archpediatrics.com)

Editor’s Note: This study was supported by a grant from the National Institutes of Health, Bethesda, Md., and MedImmune, Inc., Mountain View, Calif., which provided the investigational intranasal influenza vaccine.

For more information, contact JAMA/Archives Media Relations at 312/464-JAMA (5262) or e-mail mediarelations@jama-archives.org .

Scott Clark | EurekAlert!
Further information:
http://www.jama.com/
http://archpediatrics.com

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>