Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Depression, other psychiatric illnesses common following traumatic brain injury

06.01.2004


Many patients who experience a traumatic injury to the brain experience major depression or other psychiatric illnesses within a year after their head injuries, according to two articles in the January issue of The Archives of General Psychiatry, one of the JAMA/Archives journals.



Mood and anxiety disorders are common complications among patients who have experienced traumatic brain injury (TBI), according to the article. Studies suggest that depression is also a common psychiatric complication of TBI, however, clinical implication of major depression following TBI have not been extensively studied.

Ricardo E. Jorge, M.D., of the University of Iowa, Iowa City and colleagues studied 91 patients with TBI, and 27 patients with multiple trauma but without any evidence of central nervous system injury as controls. The patients’ conditions were evaluated at three, six and twelve months after the injury, and psychiatric diagnosis was made. Neuropsychological testing and magnetic resonance imaging (MRI) of the brain were performed at the three-month follow-up visit.


Of the 91 patients with TBI, 30 (33 percent) had major depressive disorder during the first year after their injury. Major depressive disorder was significantly more frequent among patients with TBI compared to controls. The researchers also found that patients with TBI and depression were more likely to have a history of mood and anxiety disorders than patients with TBI who did not experience depression. Of patients with TBI who also had depression, 76.7 percent also had anxiety, and 56.7 percent exhibited aggressive behavior. Major depression was also associated with worse social functioning at the six- and twelve-month follow-up, as well as reduced gray matter (a brain structure) volumes on brain scans.

(Arch Gen Psychiatry. 2004;61:42-50. Available post-embargo at archgenpsychiatry.com) Editor’s Note: This study was supported by grants from the National Institute of Mental Health, National Institutes of Health, Bethesda, Md.

In a related study in this issue of The Archives of General Psychiatry, Jesse R. Fann, M.D., M.P.H., of the University of Washington, Seattle and colleagues investigated the risk of psychiatric illness after TBI among patients in an adult health maintenance organization (HMO).

The researchers studied 939 HMO members diagnosed with TBI in 1993, compared with controls in the same HMO without TBI. They found that the prevalence of any psychiatric illness in the first year after TBI was 49 percent following moderate to severe TBI, and 34 percent following mild TBI, and 18 percent in the control group.

"Both moderate to severe and mild TBI are associated with an increased risk of subsequent psychiatric illness," writes Dr. Fann. "Whereas moderate to severe TBI is associated with a higher initial risk, mild TBI may be associated with persistent psychiatric illness."


(Arch Gen Psychiatry. 2004;61:53-61. Available post-embargo at archgenpsychiatry.com)

Editor’s Note: This study was supported by a grant from the National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Ga.

For more information, contact JAMA/Archives Media Relations at 312/464-JAMA (5262) or e-mail mediarelations@jama-archives.org .

To contact Ricardo E. Jorge, M.D., call Thomas Moore at 319-356-3945. To contact Jesse R. Fann, M.D., M.P.H., call Pam Sowers at 206-685-4232.

Thomas Moore | EurekAlert!
Further information:
http://www.jama.com/
http://archgenpsychiatry.com

More articles from Health and Medicine:

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

nachricht ASU scientists develop new, rapid pipeline for antimicrobials
14.12.2017 | Arizona State University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

Im Focus: Successful Mechanical Testing of Nanowires

With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong

Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Plasmonic biosensors enable development of new easy-to-use health tests

14.12.2017 | Health and Medicine

New type of smart windows use liquid to switch from clear to reflective

14.12.2017 | Physics and Astronomy

BigH1 -- The key histone for male fertility

14.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>