Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Passive tobacco smoke increases complications in children with sickle cell disease

17.12.2003


Physicians and researchers at the UC Davis School of Medicine and Medical Center found that children with sickle cell disease who are exposed to tobacco smoke in the home have more complications from the disease than those who live in a smoke-free environment. The study was published in the December issue of the Archives of Pediatrics and Adolescent Medicine.



"Exposure to environmental or passive tobacco smoke increased the risk of sickle cell crisis by 90 percent, and was not influenced by other factors known to increase complications, such as age of the patient or type of sickle cell disease," said Daniel C. West, associate professor of pediatrics at UC Davis and lead author of the study. "Exposure to tobacco smoke has a tremendous impact on children with sickle cell disease. In fact, the study suggests that removing passive tobacco smoke from the home might not only reduce the suffering of children with sickle cell disease, but also reduce the cost of medical care."

Sickle cell disease is a hereditary disease that affects hemoglobin, the protein in red blood cells that carries and delivers oxygen to tissues. The presence of sickle hemoglobin can lead to damaged and misshapen red blood cells that do not flow normally through blood vessels and deliver less than the normal amount of oxygen to peripheral tissues. These abnormalities can cause episodes of severe pain, known as sickle cell crises, and life-threatening damage to vital organs, such as the lungs and the brain.


Over a period of two years, researchers monitored 52 patients between the ages of 2 and 18 with several types of sickle cell disease.

Each patient or family completed an environmental survey and researchers recorded the number of sickle cell crises -- vaso-occlusive pain episodes, acute chest syndrome, stroke -- that required hospitalization.

The 22 children and adolescents who were exposed to environmental tobacco smoke experienced more than twice the number of sickle cell crises requiring hospitalization compared to those not exposed to tobacco smoke in the home.

As a secondary outcome, researchers found that the cost of hospitalization in the exposed group was more than triple the cost of hospitalization in the unexposed group.

West said, "If we can reduce smoking in family members, we may be able to significantly reduce the life-threatening complications of sickle cell disease in their children."


The UC Davis Sickle Cell Center is the only center located in inland Northern California. It serves a population of approximately 5 million people.

Copies of all news releases from UC Davis Health System are available on the Web at http://www.ucdmc.ucdavis.edu/news/.

UC Davis Medical Center is one of five University of California teaching hospitals. As the primary clinical education site for the UC Davis School of Medicine, and the only area provider of many medical services, the medical center is integral to the health and well-being of Northern Californians. Licensed for 576 beds and fully accredited, UC Davis Medical Center is home to the only level I pediatric and adult trauma center in inland Northern California, Alzheimer’s Disease Center, NCI-designated Cancer Center, Children’s Hospital, and regional burn center. As the only teaching hospital in the region, UC Davis supports a wide range of research projects that offer patients new diagnostic and treatment modalities. It’s primary care network and outpatient clinics conduct more than 800,000 patient visits each year.

Public Affairs
UC Davis Health System
4900 Broadway, Suite 1200
Sacramento, CA 95820
Phone: 916-734-9040
FAX: 916-734-9066
E-mail: publicaffairs@ucdmc.ucdavis.edu

Jennifer Conradi | UC, Davis Health System
Further information:
http://www.ucdmc.ucdavis.edu/news/children/2003/sicklecell_smoking.html
http://www.ucdmc.ucdavis.edu/news/
http://www.ucdmc.ucdavis.edu/medical_center/index

More articles from Health and Medicine:

nachricht Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Touch Displays WAY-AX and WAY-DX by WayCon

27.06.2017 | Power and Electrical Engineering

Drones that drive

27.06.2017 | Information Technology

Ultra-compact phase modulators based on graphene plasmons

27.06.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>