Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Passive tobacco smoke increases complications in children with sickle cell disease

17.12.2003


Physicians and researchers at the UC Davis School of Medicine and Medical Center found that children with sickle cell disease who are exposed to tobacco smoke in the home have more complications from the disease than those who live in a smoke-free environment. The study was published in the December issue of the Archives of Pediatrics and Adolescent Medicine.



"Exposure to environmental or passive tobacco smoke increased the risk of sickle cell crisis by 90 percent, and was not influenced by other factors known to increase complications, such as age of the patient or type of sickle cell disease," said Daniel C. West, associate professor of pediatrics at UC Davis and lead author of the study. "Exposure to tobacco smoke has a tremendous impact on children with sickle cell disease. In fact, the study suggests that removing passive tobacco smoke from the home might not only reduce the suffering of children with sickle cell disease, but also reduce the cost of medical care."

Sickle cell disease is a hereditary disease that affects hemoglobin, the protein in red blood cells that carries and delivers oxygen to tissues. The presence of sickle hemoglobin can lead to damaged and misshapen red blood cells that do not flow normally through blood vessels and deliver less than the normal amount of oxygen to peripheral tissues. These abnormalities can cause episodes of severe pain, known as sickle cell crises, and life-threatening damage to vital organs, such as the lungs and the brain.


Over a period of two years, researchers monitored 52 patients between the ages of 2 and 18 with several types of sickle cell disease.

Each patient or family completed an environmental survey and researchers recorded the number of sickle cell crises -- vaso-occlusive pain episodes, acute chest syndrome, stroke -- that required hospitalization.

The 22 children and adolescents who were exposed to environmental tobacco smoke experienced more than twice the number of sickle cell crises requiring hospitalization compared to those not exposed to tobacco smoke in the home.

As a secondary outcome, researchers found that the cost of hospitalization in the exposed group was more than triple the cost of hospitalization in the unexposed group.

West said, "If we can reduce smoking in family members, we may be able to significantly reduce the life-threatening complications of sickle cell disease in their children."


The UC Davis Sickle Cell Center is the only center located in inland Northern California. It serves a population of approximately 5 million people.

Copies of all news releases from UC Davis Health System are available on the Web at http://www.ucdmc.ucdavis.edu/news/.

UC Davis Medical Center is one of five University of California teaching hospitals. As the primary clinical education site for the UC Davis School of Medicine, and the only area provider of many medical services, the medical center is integral to the health and well-being of Northern Californians. Licensed for 576 beds and fully accredited, UC Davis Medical Center is home to the only level I pediatric and adult trauma center in inland Northern California, Alzheimer’s Disease Center, NCI-designated Cancer Center, Children’s Hospital, and regional burn center. As the only teaching hospital in the region, UC Davis supports a wide range of research projects that offer patients new diagnostic and treatment modalities. It’s primary care network and outpatient clinics conduct more than 800,000 patient visits each year.

Public Affairs
UC Davis Health System
4900 Broadway, Suite 1200
Sacramento, CA 95820
Phone: 916-734-9040
FAX: 916-734-9066
E-mail: publicaffairs@ucdmc.ucdavis.edu

Jennifer Conradi | UC, Davis Health System
Further information:
http://www.ucdmc.ucdavis.edu/news/children/2003/sicklecell_smoking.html
http://www.ucdmc.ucdavis.edu/news/
http://www.ucdmc.ucdavis.edu/medical_center/index

More articles from Health and Medicine:

nachricht Vanishing capillaries
23.03.2017 | Technische Universität München

nachricht How prenatal maternal infections may affect genetic factors in Autism spectrum disorder
22.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

When Air is in Short Supply - Shedding light on plant stress reactions when oxygen runs short

23.03.2017 | Life Sciences

Researchers use light to remotely control curvature of plastics

23.03.2017 | Power and Electrical Engineering

Sea ice extent sinks to record lows at both poles

23.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>