By tailoring the dosage of chemotherapy to each individual patient, the treatment of breast cancer could be improved considerably. This is shown in a dissertation by Uppsala researcher Henrik Lindman at Uppsala University in Sweden. The method has proven to yield excellent results in clinical tests.
The dissertation reports that an alternative way of tailoring the dosage of chemotherapy has been studied and found to work. If the advantages of this method compared to standard treatment can be verified in the follow-up study that has just been completed on more than 1,500 patients in Sweden and Denmark, we may be facing a more extensive change in the treatment of cancer, one that reaches far beyond the sphere of breast cancer. One clear advantage of the method, apart from fewer side-effects and less risk of under-dosage, is that it should provide a way of determining the value of new chemotherapies, since it is probable that tailored dosages will prevent improper dosage regimens to a greater extent than previously.
In treating cancer, the dosage of chemotherapy is normally determined on the basis of the body surface area of the patient, which factors in height and weight. This method has proven to be insufficient when it comes to differences among patients in the amount of chemotherapy in the blood. Some patients receive overdoses with severe side-effects as a result, while others receive under-dosed regimens that risk leaving the tumor insufficiently treated.
Anneli Waara | alfa
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
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The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.
Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...
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