Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Combining various magnetic resonance imaging techniques may help improve breast cancer detection

12.12.2003


Researchers at Johns Hopkins say that combining various types of magnetic resonance (MR) imaging techniques more accurately sorts cancers from benign masses in breast tissues than any single imaging techniques. Their findings are presented in the October issue of Radiology.



Magnetic resonance imaging scanners can be calibrated to take images that highlight a specific type of human tissue. For example, so-called T1-weighted imaging sequences are best at imaging fatty tissues, while T2-weighted sequences best show fluids, like those found inside cysts. Additionally, 3-dimensional MR imaging can help define the size and shape of tumors. Contrast agents, dyes injected into patients prior to imaging to concentrate in the tumor and make it more visible, further enhance MR images similar to the way dye in water helps highlight the "veins" in celery stalks.

In their study, Hopkins researchers combined T1, T2 and 3-D imaging techniques, with and without contrast agents, on 36 subjects. Eighteen already had been diagnosed with benign breast lesions, and 18 with breast cancer. The researchers reviewed the results of the combined images without knowing which images came from which patient.


The combined, or multiparametric MRI technique, was able to identify and characterize breast lesion tissue clusters in all 36 patients, revealing which were benign and which were malignant. In addition, the multiparametric technique was even more powerful when used with contrast agents, providing more precise differentiation between the cancerous and non-cancerous tissue than the same images without contrast.

"Each individual imaging modality has its advantages," says Michael Jacobs, Ph.D., the lead researcher for the study at the Hopkins Department of Radiology. "When all these techniques are combined into one data set, you can achieve an approach that shows the characteristics of a lesion not normally available using just one imaging technique."

Jacobs notes that while his study appears to demonstrate the feasibility of using a combined imaging approach to identifying breast tumors, larger studies are needed to determine if the approach might be useful for studying the molecular dynamics of breast cancer tumors.

"It’s known that certain compounds, such as choline and sodium ions, tend to concentrate in cancer cells," Jacobs says. "We are now investigating whether multiparametric MR imaging might be effective in imaging intracellular compounds within breast tumors. If so, this will enable a comprehensive assessment of the tumor environment."

Gary Stephenson | EurekAlert!
Further information:
http://www.hopkinsmedicine.org

More articles from Health and Medicine:

nachricht 'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS

nachricht New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

Im Focus: Autonomous 3D scanner supports individual manufacturing processes

Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).

Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Fingerprints of quantum entanglement

16.02.2018 | Information Technology

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers

16.02.2018 | Health and Medicine

Hubble sees Neptune's mysterious shrinking storm

16.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>