Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Combining various magnetic resonance imaging techniques may help improve breast cancer detection


Researchers at Johns Hopkins say that combining various types of magnetic resonance (MR) imaging techniques more accurately sorts cancers from benign masses in breast tissues than any single imaging techniques. Their findings are presented in the October issue of Radiology.

Magnetic resonance imaging scanners can be calibrated to take images that highlight a specific type of human tissue. For example, so-called T1-weighted imaging sequences are best at imaging fatty tissues, while T2-weighted sequences best show fluids, like those found inside cysts. Additionally, 3-dimensional MR imaging can help define the size and shape of tumors. Contrast agents, dyes injected into patients prior to imaging to concentrate in the tumor and make it more visible, further enhance MR images similar to the way dye in water helps highlight the "veins" in celery stalks.

In their study, Hopkins researchers combined T1, T2 and 3-D imaging techniques, with and without contrast agents, on 36 subjects. Eighteen already had been diagnosed with benign breast lesions, and 18 with breast cancer. The researchers reviewed the results of the combined images without knowing which images came from which patient.

The combined, or multiparametric MRI technique, was able to identify and characterize breast lesion tissue clusters in all 36 patients, revealing which were benign and which were malignant. In addition, the multiparametric technique was even more powerful when used with contrast agents, providing more precise differentiation between the cancerous and non-cancerous tissue than the same images without contrast.

"Each individual imaging modality has its advantages," says Michael Jacobs, Ph.D., the lead researcher for the study at the Hopkins Department of Radiology. "When all these techniques are combined into one data set, you can achieve an approach that shows the characteristics of a lesion not normally available using just one imaging technique."

Jacobs notes that while his study appears to demonstrate the feasibility of using a combined imaging approach to identifying breast tumors, larger studies are needed to determine if the approach might be useful for studying the molecular dynamics of breast cancer tumors.

"It’s known that certain compounds, such as choline and sodium ions, tend to concentrate in cancer cells," Jacobs says. "We are now investigating whether multiparametric MR imaging might be effective in imaging intracellular compounds within breast tumors. If so, this will enable a comprehensive assessment of the tumor environment."

Gary Stephenson | EurekAlert!
Further information:

More articles from Health and Medicine:

nachricht Advanced analysis of brain structure shape may track progression to Alzheimer's disease
26.10.2016 | Massachusetts General Hospital

nachricht Indian roadside refuse fires produce toxic rainbow
26.10.2016 | Duke University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel light sources made of 2D materials

Physicists from the University of Würzburg have designed a light source that emits photon pairs. Two-photon sources are particularly well suited for tap-proof data encryption. The experiment's key ingredients: a semiconductor crystal and some sticky tape.

So-called monolayers are at the heart of the research activities. These "super materials" (as the prestigious science magazine "Nature" puts it) have been...

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Prototype device for measuring graphene-based electromagnetic radiation created

28.10.2016 | Power and Electrical Engineering

Gamma ray camera offers new view on ultra-high energy electrons in plasma

28.10.2016 | Physics and Astronomy

When fat cells change their colour

28.10.2016 | Life Sciences

More VideoLinks >>>