Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Gas bubbles are taken under control

17.11.2003


The system developed by the Moscow scientists with the financial assistance of the Russian Foundation for Basic Research and the Foundation for Assistance to Small Innovative Enterprises will instantly allow to detect and measure gas micro-bubbles being formed in blood inside the pump oxygenator. A small device which looks like some kind of a bracelet on the arterial line of the pump oxygenator and is connected to the computer will be recording all bubbles, searching for potentially dangerous ones and will ensure the timely opportunity to get rid of them.



A patient on the operating table is exposed to numerous risks, especially if the operation is so complex, that extracorporeal circulation is required. One of the dangers is a risk of embolism by a gas bubble, which may occur in the process of blood circulation in the pump oxygenator. It is not always clear why the gas bubbles originate, but they do almost in all the cases. The smaller ones, less than 10 microns in diameter are not particularly dangerous, as they quite rapidly dissolve by themselves. As for bigger bubbles, they may plug in a vessel like a cork, thus disrupting normal blood circulation and causing very bad problems for the organism.

In order to avoid such consequences, it is necessary to trace all the bubbles formed in a pump oxygenator, detect the biggest ones as the most dangerous and get rid of them. The matter is that it has only been possible so far to apply a qualitative approach to this problem, but the scientists have not had any clue to solving it at the quantitative level - to detect gas bubbles in blood and to determine their number and size. In other words, the scientists were unable to distribute the bubbles by size.


However, this problem can soon be solved due to the effort of the scientists from the Moscow research-and-production company ‘BIOSS’. They developed a special system of detecting micro-bubbles on the arterial line of the pump oxygenator to perform extracorporeal circulation.

It consists of several parts. The core of the device is an electronic unit with the ultrasonic detector, which reminds a bracelet, but is very intelligent. Its action is based on the Doppler effect – the fact that the frequency of oscillation or the radiation wave length is changing when re-echoed from a moving object. Omitting technical details, the essence is that the generator creates a continuous ultrasonic wave, it is reflected from the bubbles and the detector, in its turn, catches the echoed signal.

Then an analog-to-digital converter ‘translates’ the assisted signal into the computer language, making the signal digital and then it is further transmitted to the data processing, storage and display unit. This way it is possible to display at any time a bar chart at the PC screen, showing how many gas bubbles are moving in blood flow inside the pump oxygenator and to evaluate their sizes.

So far, there has been built only one test copy of this remarkable device. The developers are currently testing it on a special calibration test bench. The device was especially developed and built for the purpose of creating gas bubbles of the predetermined size in the liquid imitating blood. First, it was necessary to calibrate the system, and the scientists did not have the standard. They had to develop it separately.

The system successfully underwent the first tests both at the test bench and at the real pump oxygenator. “Our system has demonstrated all the capabilities we expected to get”, said Tengiz Mosidze, the project manager and leading engineer. It quickly records gas bubbles ranging from 10 to 400 microns in diameter and accurately determines their sizes. We still need to perform medical tests. Currently, we are developing the algorithm of the computer program which will allow to analyze the situation and evaluate the probability of embolism. And for the future project we have plans to develop a system capable not only to detect dangerous bubbles in blood, but also to remove them automatically.”

Sergey Komarov | alfa
Further information:
http://www.informnauka.ru

More articles from Health and Medicine:

nachricht Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State

nachricht NTU scientists build new ultrasound device using 3-D printing technology
07.12.2016 | Nanyang Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Closing the carbon loop

08.12.2016 | Life Sciences

Applicability of dynamic facilitation theory to binary hard disk systems

08.12.2016 | Physics and Astronomy

Scientists track chemical and structural evolution of catalytic nanoparticles in 3-D

08.12.2016 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>