Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers find genetic clue to cancer relapse

13.11.2003


Cancer researchers at Perth’s Telethon Institute for Child Health Research (TICHR) have developed a new test that can rapidly detect the loss of genes in cancer cells, paving the way for more targeted and effective treatments for patients.



Australian Cancer Technology (AustCancer, ASX:ACU) today announced that it has entered into a partnership agreement with the Institute to commercialise this novel technology and bring it to the market as quickly as possible.

Professor Ursula Kees, who heads the Children’s Leukaemia and Cancer Research Division at TICHR, said the development of a fast, simple gene test could significantly improve patient outcomes.


"Our research in a group of cancer patients has shown that those patients with cancer cells that have lost a specific tumour suppressor gene are at greater risk of relapse," she said.

"If their doctors can determine the genetic makeup of the cancer at an early stage, then they will have a very important indicator of the type of treatment that will be most effective."

"Current methods for testing the loss of genes in cancer cells are expensive and relatively slow. The new technology that we have developed is fast, simple and can be applied at low cost - in fact it uses standard equipment found in most diagnostic labs."

Professor Kees said in studies on children with acute lymphoblastic leukaemia (ALL), which were published in the prestigious journal ’Blood’, her team had shown that this technology is effective in measuring the deletion of an important tumour suppressor gene. The studies also showed that the gene’s absence pointed to a 11-fold higher risk of relapse.

"Testing cancer cells to determine whether a gene is missing has always been considered very difficult because patient specimens always contain normal cells, and the genetic differences that we’re looking for are very subtle. This new technology can detect those very small differences."

Paul Hopper, managing director of AustCancer said his company would be determining the most appropriate commercial model by which the test can be rapidly brought to the market.

"We believe that, as medical science’s understanding of the role of genes in cancer grows, an inexpensive, quick and routine gene test will become essential in the diagnosis of many types of cancer. The technology is patented and we have embarked on a research program with the Institute to expand its utility to other important cancer genes."

Director of the Telethon Institute for Child Health Research, Professor Fiona Stanley, said the Institute was delighted to partner with AustCancer on this discovery because of their strong credentials in the field.

"It’s important that we make sure that the benefits of our research are seen by the patients as soon as possible. This partnership will ensure that we can now take this discovery to the next stage of development."

PLEASE DIRECT ENQUIRIES TO:

Liz Chester
Media Liaison Manager
Telethon Institute for Child Health Research
Phone: +61 409 988 530

Paul Hopper
Managing Director
Australian Cancer Technology
Phone: +61 407 118 366 or +61 2 9252 6899

Mike Feehan
Monsoon Communications
Phone: +61 3 9620 3333

| Monsoon Communications
Further information:
http://www.ichr.uwa.edu.au
http://www.austcancer.com.au

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

New technology for mass-production of complex molded composite components

23.01.2017 | Process Engineering

Quantum optical sensor for the first time tested in space – with a laser system from Berlin

23.01.2017 | Physics and Astronomy

The interactome of infected neural cells reveals new therapeutic targets for Zika

23.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>