Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers find genetic clue to cancer relapse

13.11.2003


Cancer researchers at Perth’s Telethon Institute for Child Health Research (TICHR) have developed a new test that can rapidly detect the loss of genes in cancer cells, paving the way for more targeted and effective treatments for patients.



Australian Cancer Technology (AustCancer, ASX:ACU) today announced that it has entered into a partnership agreement with the Institute to commercialise this novel technology and bring it to the market as quickly as possible.

Professor Ursula Kees, who heads the Children’s Leukaemia and Cancer Research Division at TICHR, said the development of a fast, simple gene test could significantly improve patient outcomes.


"Our research in a group of cancer patients has shown that those patients with cancer cells that have lost a specific tumour suppressor gene are at greater risk of relapse," she said.

"If their doctors can determine the genetic makeup of the cancer at an early stage, then they will have a very important indicator of the type of treatment that will be most effective."

"Current methods for testing the loss of genes in cancer cells are expensive and relatively slow. The new technology that we have developed is fast, simple and can be applied at low cost - in fact it uses standard equipment found in most diagnostic labs."

Professor Kees said in studies on children with acute lymphoblastic leukaemia (ALL), which were published in the prestigious journal ’Blood’, her team had shown that this technology is effective in measuring the deletion of an important tumour suppressor gene. The studies also showed that the gene’s absence pointed to a 11-fold higher risk of relapse.

"Testing cancer cells to determine whether a gene is missing has always been considered very difficult because patient specimens always contain normal cells, and the genetic differences that we’re looking for are very subtle. This new technology can detect those very small differences."

Paul Hopper, managing director of AustCancer said his company would be determining the most appropriate commercial model by which the test can be rapidly brought to the market.

"We believe that, as medical science’s understanding of the role of genes in cancer grows, an inexpensive, quick and routine gene test will become essential in the diagnosis of many types of cancer. The technology is patented and we have embarked on a research program with the Institute to expand its utility to other important cancer genes."

Director of the Telethon Institute for Child Health Research, Professor Fiona Stanley, said the Institute was delighted to partner with AustCancer on this discovery because of their strong credentials in the field.

"It’s important that we make sure that the benefits of our research are seen by the patients as soon as possible. This partnership will ensure that we can now take this discovery to the next stage of development."

PLEASE DIRECT ENQUIRIES TO:

Liz Chester
Media Liaison Manager
Telethon Institute for Child Health Research
Phone: +61 409 988 530

Paul Hopper
Managing Director
Australian Cancer Technology
Phone: +61 407 118 366 or +61 2 9252 6899

Mike Feehan
Monsoon Communications
Phone: +61 3 9620 3333

| Monsoon Communications
Further information:
http://www.ichr.uwa.edu.au
http://www.austcancer.com.au

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>