According to Professor Matti Haltia, a new form of the hereditary disorder Alzheimer’s disease, which paralyses the lower extremities of its victims, has been discovered in Finland. This disease has since also been discovered in many other countries. The disorder is caused by a new type of genetic defect, which leads to the accumulation of cotton-wool plaque in the cerebral cortex. These cotton-wool plaques lack the traditional Alzheimer plaques, i.e. an amyloid core. This discovery is altering the understanding of how Alzheimer’s disease is formed. Haltia’s research was part of the Academy of Finland’s Research Programme on Ageing. Genetic research was conducted in co-operation with American professor John Hardy, who was the first to discover the genetic defect that causes Alzheimer’s disease in 1991.
Professor Haltia and his research group have shown that Alzheimer’s disease is even more common among people over 85 years of age than previously thought. Furthermore, the research found that a certain form of the LPL protein protects against cerebral infarction. This represents the first known common hereditary factor related to cerebral infarction.
Haltia’s group research has also proven that the ’Pohjoinen’ epilepsy discovered in the Kainuu region of Finland is a new NCL disease. The genetic defect that causes the disease was identified by the research group headed by Professor Anna-Elina Lehesjoki. Even in Finland, NCL diseases are some of the most common hereditary brain disorders among children. They lead to the accumulation of lipofuscin (ageing pigment) type material in nerve cells and the destruction of nerve cells. In this sense they may serve as models of ageing.
Anita Westerback | alfa
Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences