Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Systolic better than diastolic or pulse blood pressure as indicator of mortality risk

04.11.2003


Rising systolic blood pressure is the clearest indicator for increased risk of death compared to other blood pressure measurements, according to researchers at the Johns Hopkins Bloomberg School of Public Health. Their evaluation of blood pressure measurements and mortality risk found that diastolic and pulse pressure measurements were weaker indicators of mortality risk and their effect was more dependent on age and other factors. The study appears in the November 4, 2003, edition of the Annals of Internal Medicine.



Systolic pressure, which is the higher number and first number in a blood pressure reading, measures the force of blood in the arteries as the heart contracts to push blood through the body. Doctors consider a systolic blood pressure greater than 120 mm Hg (millimeters of mercury) as unhealthy and can lead to heart disease, stroke and vascular diseases of the legs. Diastolic pressure, the lower number, measures the pressure as the heart relaxes to fill with blood. A diastolic pressure greater than 80 mm Hg is also considered unhealthy. Pulse pressure is the difference between the diastolic and systolic readings.

"There is some controversy in the medical community over whether the monitoring of systolic, diastolic, or pulse pressure should be the focus in treating hypertension. Our study shows that an increased systolic reading is most closely associated with an increased risk of death," said lead investigator Eliseo Guallar, MD, DrPH, an assistant professor in the School’s Department of Epidemiology.


The study included 7,830 white and African American adults age 30 to 74 that took part in the Second National Health and Nutrition Examination Survey (NHANES II) from 1976 to 1992. All of the participants were free of an obvious heart disease. Blood pressure was measured three times at enrollment. Of the 1,588 participants who died, 582 died of cardiovascular disease.

Dr. Guallar and his colleagues studied the effects of high systolic and diastolic blood pressure simultaneously and found a direct and consistent correlation between increased systolic blood pressure and an increased risk of death from cardiovascular disease and for all other causes among all of the study participants. Increased diastolic pressure over 80 mm Hg was also associated with an increased risk of death. However, for people under 65, the risk of death remained the same for diastolic reading of 80 mm Hg or lower. For participants over 65 years of age, the risk of death increased with low diastolic pressure.

The researchers found a complex association between pulse pressure and mortality. Increasing pulse pressure caused by increased systolic pressure was associated with an increased risk of mortality. Increased pulse pressure caused by increased diastolic pressure could be associated with increased risk, decreased risk, and no change in the risk of mortality.

"Pulse pressure alone, without appropriate attention to systolic and diastolic blood pressure components, is an inadequate indicator of mortality risk," said Dr. Guallar.


"Systolic Blood Pressure, Diastolic Blood Pressure, and Pulse Pressure: An Evaluation of Their Joint Effect on Mortality" was written by Roberto Pastor-Barriuso, PhD; José R. Banegas, MD, PhD; Javier Damián, MD, PhD; Lawrence J. Appel, MD, MPH; and Eliseo Guallar, MD, MPH.

Funding was provided by the Instituto de Salud Carlos III, Madrid, Spain. Study investigators work at the National Center for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain; Universidad Autónoma de Madrid, Spain; and Johns Hopkins Medical Institutions.

Kenna Brigham | EurekAlert!
Further information:
http://www.jhsph.edu/
http://www.jhsph.edu/Press_Room

More articles from Health and Medicine:

nachricht Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>