Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pneumonia caused cellular immunity damage is reversible

28.10.2003


Cellular immunity amongst the elderly with non-hospital acquired pneumonia diminishes both quantitatively and qualitatively. Nevertheless, the cellular immunosupression detected in these patients is reversible and improves with time.

30% mortality

In the past few decades there has been a significant and progressive increase in the number of elderly people and so there is a greater number of illnesses such as pneumonia. The problem arises because pneumonia amongst the elderly (PAE) has a high mortality rate – about 30% - the prime cause of death through infectious disease amongst the elderly.



The underlying causes of these rates are related to immunosenescence, simply the natural process of ageing and the deterioration of the immune system. A deterioration which is augmented by chronic or acute pathological events such as pneumonia and also, apparently, by malnutrition.

This is why acute immunosupression in addition to the process of immunosenescence may well affect the mortality rates of PAE and of patients who have overcome pneumonia.

It is to this aspect that doctor Humberto Mendoza has directed his thesis having, as its objective, analysis of the complete immunological situation of the non-hospital acquired pneumonia in the elderly patient who has to be admitted to hospital. Moreover, the analytical data about immunity on hospitalisation were compared with that after release, with the aim of studying possible post-hospital recovery.

Finally, it was wished that the effect of nutrition on ease and quality of life be monitored and so, nutritional data was studied for admission and post hospital periods in order to see if nutrition influences the recovery and survival of the patient.

Patients hospitalised at the Virgen del Camino Hospital

In order to carry out the study, a sample patients over 65 with non-hospital acquired pneumonia and admitted to the Internal Medicine wing of the Virgen del Camino Hospital between 1996 and 1998 was taken.

Initial data taken on these patients included a study of general aspects - analytical, microbiological, radiological and other variables related to immunity, nutrition or Kataz and Karnofsky life quality index values. Furthermore, follow-up studies on these values were carried out.

Humberto Mendoza has analysed these data and drawn the conclusion that, although, cellular immunity amongst the elderly with non-hospital acquired pneumonia clearly diminishes both quantitatively and qualitatively, this immunosupression is reversible and improves with time.


Finally, no relation has been found between the immunity data and nutrition parameters. On the other hand, malnutrition has a significant influence in the mortality of patients admitted, while it does not appear to influence immunity values in any marked way.

Iñaki Casado Redin | Basque research
Further information:
http://www.basqueresearch.com/
http://www.unavarra.es

More articles from Health and Medicine:

nachricht A whole-body approach to understanding chemosensory cells
13.12.2017 | Tokyo Institute of Technology

nachricht Research reveals how diabetes in pregnancy affects baby's heart
13.12.2017 | University of California - Los Angeles Health Sciences

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

Im Focus: Successful Mechanical Testing of Nanowires

With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong

Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

A whole-body approach to understanding chemosensory cells

13.12.2017 | Health and Medicine

Water without windows: Capturing water vapor inside an electron microscope

13.12.2017 | Physics and Astronomy

Cellular Self-Digestion Process Triggers Autoimmune Disease

13.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>