Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pneumonia caused cellular immunity damage is reversible

28.10.2003


Cellular immunity amongst the elderly with non-hospital acquired pneumonia diminishes both quantitatively and qualitatively. Nevertheless, the cellular immunosupression detected in these patients is reversible and improves with time.

30% mortality

In the past few decades there has been a significant and progressive increase in the number of elderly people and so there is a greater number of illnesses such as pneumonia. The problem arises because pneumonia amongst the elderly (PAE) has a high mortality rate – about 30% - the prime cause of death through infectious disease amongst the elderly.



The underlying causes of these rates are related to immunosenescence, simply the natural process of ageing and the deterioration of the immune system. A deterioration which is augmented by chronic or acute pathological events such as pneumonia and also, apparently, by malnutrition.

This is why acute immunosupression in addition to the process of immunosenescence may well affect the mortality rates of PAE and of patients who have overcome pneumonia.

It is to this aspect that doctor Humberto Mendoza has directed his thesis having, as its objective, analysis of the complete immunological situation of the non-hospital acquired pneumonia in the elderly patient who has to be admitted to hospital. Moreover, the analytical data about immunity on hospitalisation were compared with that after release, with the aim of studying possible post-hospital recovery.

Finally, it was wished that the effect of nutrition on ease and quality of life be monitored and so, nutritional data was studied for admission and post hospital periods in order to see if nutrition influences the recovery and survival of the patient.

Patients hospitalised at the Virgen del Camino Hospital

In order to carry out the study, a sample patients over 65 with non-hospital acquired pneumonia and admitted to the Internal Medicine wing of the Virgen del Camino Hospital between 1996 and 1998 was taken.

Initial data taken on these patients included a study of general aspects - analytical, microbiological, radiological and other variables related to immunity, nutrition or Kataz and Karnofsky life quality index values. Furthermore, follow-up studies on these values were carried out.

Humberto Mendoza has analysed these data and drawn the conclusion that, although, cellular immunity amongst the elderly with non-hospital acquired pneumonia clearly diminishes both quantitatively and qualitatively, this immunosupression is reversible and improves with time.


Finally, no relation has been found between the immunity data and nutrition parameters. On the other hand, malnutrition has a significant influence in the mortality of patients admitted, while it does not appear to influence immunity values in any marked way.

Iñaki Casado Redin | Basque research
Further information:
http://www.basqueresearch.com/
http://www.unavarra.es

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>