Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Improving the quality of life for larynx cancer patients

21.10.2003


Currently, voice rehabilitation of larynx cancer patients is performed by inserting a one-way shunt valve between trachea and oesophagus that prevents food and liquid from entering the trachea. Pressing the tracheal opening with a finger forces exhaled air through the shunt valve to the oesophagus, where soft tissue structures serve as a substitute voice. However, the voice is in many cases of poor quality and the process creates a mental barrier during speaking, as patients have to literally point at their handicap.



The NEWVOICE project aims to improve the quality of life for laryngectomees by developing a new voice-producing shunt prosthesis that is able to produce a voice with sufficient loudness, adjustable fundamental frequency and natural intonation.

Dr. Bart Verkerke, Project Manager of the Department of BioMedical Engineering at the main partner, the University of Groningen, describes how the partners initiated this work in a previous EUREKA project. “Most of the NEWVOICE participants were involved in project E! 723 ARTIFICIAL LARYNX, during which we gained a lot of the expertise in medical devices to improve the rehabilitation process that will be used in this project.”


Tackling problems
The new voice-producing element that was inspired by the lips of a trumpet player is working well technically, but poses a prototyping problem as it is too big to fit into an existing shunt valve. Work is progressing to try to develop a small voice-producing element that still has the proper frequency characteristics. At the same time, the project also aims to develop a new fixation technique, the so-called tissue connector, which allows for a larger shunt valve.

Six different concepts for the tissue connector that fastens the shunt valve in place are being tested as “it was impossible to determine which of the alternatives was the most appropriate. We will perform a pilot animal study to test them and choose the most effective,” says Verkerke.

A critical problem facing the project team is that food and fluid passing the shunt valve stimulates the formation of a biofilm. “This causes the shunt valve to malfunction, making it necessary to replace the shunt valve frequently, on average every four months,” explains Dr Mark Waters, Senior Lecturer in Biomaterials at Cardiff Dental School. “The task of the UK partners is to develop silicone rubber materials which are less susceptible to biofilm formation.”

The project has already developed coatings that slow down or prevent biofilm adhesion that could extend the life of a shunt valve for some patients considerably.

According to Verkerke, “the major challenges lying ahead include finding a material that can resist all yeasts and bacteria, proving that the concept of the tissue connector works, and finding a voice-producing element small enough to fit into a shunt valve.”

Nicola Vatthauer | alfa
Further information:
http://www.eureka.be

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>