Transplant surgeon Oscar H. Grandas (left) and reproductive immunologist Anatolij Horuzsko are looking at a molecule expressed early in pregnancy that may provide a better way to help transplanted organs survive.
A molecule expressed in the earliest stages of pregnancy that vanishes when the baby is born seems to keep some cells responsible for directing the immune system in an immature and accepting stage, Medical College of Georgia researchers says.
Their finding that the molecule HLA-G helps make dendritic cells – which work like air-traffic controllers for the immune system – tolerant helps explain how a fetus, with genes from both parents, can avoid rejection by the mother’s immune system.
And it has them optimistic that the natural mechanism could be replicated to help preserve a transplanted heart or kidney.
Toni Baker | EurekAlert!
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
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