Hereditary Alzheimer’s disease has been shown to be the result of mutations in certain specific genes. Other cases of Alzheimer’s are also assumed to be traceable to the influence of a number of still unidentified genes. It is probable that these genes are located in a large area on chromosome 10q, which contains more than 100 genes.
Working with researchers in Gothenburg and Los Angeles, scientists at the Karolinska Institute in Stockholm, Sweden have now narrowed down the area of interest on chromosome 10 to include only three genes. The results are being published in the journal Human Mutation Online, September 24, 2003.
One of these highly interesting genes codes for the protein insulin degrading enzyme (IDE). This protein is a strong candidate for a role in Alzheimer’s owing to its biological function -- it breaks down extracellular amyloid-beta protein, one of the substances that make up the senile plaque that is formed in Alzheimer’s.
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For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...
Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...
On 15 March, the AWI research aeroplane Polar 5 will depart for Greenland. Concentrating on the furthest northeast region of the island, an international team...
The world’s second-largest ice shelf was the destination for a Polarstern expedition that ended in Punta Arenas, Chile on 14th March 2018. Oceanographers from...
At the 2018 ILA Berlin Air Show from April 25–29, the Fraunhofer Institute for Laser Technology ILT is showcasing extreme high-speed Laser Material Deposition (EHLA): A video documents how for metal components that are highly loaded, EHLA has already proved itself as an alternative to hard chrome plating, which is now allowed only under special conditions.
When the EU restricted the use of hexavalent chromium compounds to special applications requiring authorization, the move prompted a rethink in the surface...
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