An unusual collaboration between a University of Iowa cardiologist and cancer biologists at the Holden Comprehensive Cancer Center at the UI, the Scripps Research Institute in California and Kanagawa Cancer Center Hospital and Research Center in Japan utilized a multidisciplinary approach to learn more about how aggressive cancer cells function and how they differ from poorly aggressive cancer cells. The study, which appears in the Sept. 1 issue of Cancer Research, may also suggest potential new therapeutic targets for cancer treatment.
MARY J. C. HENDRIX, Ph.D.
Kate Daum Research Professor and Head
Previous studies have found that aggressive tumor cells express genes that are more normally associated with other cell types, including endothelial cells that line blood vessels. Also, aggressive cancer cells are able to form vascular-like, fluid-conducting networks, an ability known as vasculogenic mimicry that resembles the behavior of embryonic cells that form primitive vascular networks.
Patients tumors that have fluid-conducting networks are much more aggressive than tumors that do not have those networks.
A 'half-hearted' solution to one-sided heart failure
24.11.2017 | Boston Children's Hospital
New study points the way to therapy for rare cancer that targets the young
22.11.2017 | Rockefeller University
High-precision measurement of the g-factor eleven times more precise than before / Results indicate a strong similarity between protons and antiprotons
The magnetic moment of an individual proton is inconceivably small, but can still be quantified. The basis for undertaking this measurement was laid over ten...
Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
24.11.2017 | Physics and Astronomy
24.11.2017 | Health and Medicine
24.11.2017 | Earth Sciences