Recoverying from third and fourth degree burns, the most damaging types, is a slow and painful process that inevitably leaves excessive scar tissue. Russian researchers have developed a pharmacological enzyme preparation to accelerate the debridement process and wound healing, which reduces the preparation time for grafting and diminishes scarring.
Their product, called ENZYCOL, is a mixture of collagenases from the Kamchatka crab that rapidly dissolves the dense collagen matrix of necrotic skin forming after a burn. By removing this non-living tissue, ENZYCOL promotes the healing of the surrounding healthy tissue, a vital process for preventing the onset of infection. The debridement period for burns pre-treated with the crab collagenase mixture is 2 days shorter than with traditional enzyme therapies such as trypsin.
The research team consisted of scientists from the Russian Cardiology Research Center in Moscow and the Research Center of Toxicology and Hygienic Regulation of Biopreparations in Serpukhov (Moscow Region). Seventy-one scientists and technical staff, of which forty represented former biological and chemical weapons experts, participated in two ISTC projects to develop this technology. They began their work in 1999 to develop the powder preparation and confirm its safety and effectiveness in vitro. In the follow-up project, which began in 2002 and is currently going on, the scientists modified the method for preparing ENZYCOL to make it suitable for pilot scale production. They also performed pre-clinical trials on laboratory animals, which proved that the enzyme cocktail is non-toxic, non-mutagenic, and non-irritating on skin.
Alexander Ivanchenko | alfa
PET imaging tracks Zika virus infection, disease progression in mouse model
20.09.2017 | US Army Medical Research Institute of Infectious Diseases
'Exciting' discovery on path to develop new type of vaccine to treat global viruses
18.09.2017 | University of Southampton
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
20.09.2017 | Life Sciences
20.09.2017 | Power and Electrical Engineering
20.09.2017 | Physics and Astronomy