Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Aspirin could reduce the risk of deadly infections

18.07.2003


Adding to the long list of the benefits of aspirin, researchers have found that it is responsible for reducing toxic bacteria associated with serious infections. A study led by Dartmouth Medical School describes how salicylic acid-produced when the body breaks down aspirin-disrupts the bacteria´s ability to adhere to host tissue, reducing the threat of deadly infections.



The investigation, which appears in the July 15 issue of the Journal of Clinical Investigation, focused on the bacterium Staphylococcus aureus, and its role in infections in animal tissue. S. aureus is a leading cause of serious systemic (often referred to as staph) infections and abscesses.

"Our research shows that salicylic acid, a byproduct of aspirin, impacted the stress system of the bacteria and reduced its ability to cause infection," said lead author Dr. Ambrose Cheung, a professor of microbiology and immunology at Dartmouth Medical School.


By disrupting this stress system, aspirin reduced the bacteria´s capacity to adhere to host tissue. In addition, the salicylic acid disrupted the ability of S. aureus to produce toxins, which the bacteria require to propagate and spread to other tissue. As a result, the animals treated with aspirin have smaller abscesses and they have fewer number of bacteria in the infection. Aspirin did not cure it, notes Cheung, but it reduced the ability of the bacteria to cause infection.

The S. aureus bacteria are also responsible for sepsis, a blood poisoning disease that strikes 750,000 people in the US annually and is the leading cause of death in America´s non-coronary intensive care units. Cases of sepsis are growing in number each year and are becoming increasingly resistant to antibiotics, making aspirin a possibly invaluable option for treatment.

"The fact that aspirin has been used for pain treatment, to reduce mortality due to heart attacks, and can possibly reduce the risks of infection is incredible," said Cheung. "We look forward to conducting future tests with aspirin in conjunction with antibiotic therapy."

Andy Nordhoff | EurekAlert!
Further information:
http://www.dartmouth.edu

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Electrode materials from the microwave oven

19.10.2017 | Materials Sciences

New material for digital memories of the future

19.10.2017 | Materials Sciences

Physics boosts artificial intelligence methods

19.10.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>