Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Scientists focusing on how exercise raises immunity

03.07.2003


An increasing number of doctors and other health experts have been encouraging older adults to rise from their recliners and go for a walk, a bike ride, a swim, or engage in just about any other form of physical activity as a defense against the potentially harmful health consequences of a sedentary lifestyle.



"Exercise is touted as a panacea for older adults," said Jeffrey Woods, a kinesiology professor at the University of Illinois at Urbana-Champaign, who noted that fitness programs are routinely recommended for people with various health problems -- from diabetes to heart disease.

Health experts generally recognize that this population benefits from physical fitness, he said. What they don’t know is why exercise appears to have certain preventive and restorative health effects. Also unknown is what -- if any -- relationship exists between exercise and immune functioning.


"Despite the numerous benefits of exercise -- for example, improving cardiovascular and muscular fitness -- we know very little about how exercise affects the immune systems of older adults," Woods said. "Good, bad or indifferent, this information could have important public health consequences for our aging population." For that reason, Woods and colleagues in the university’s kinesiology department are conducting research that seeks to establish the link between exercise training and immune function. The field, he said, is still in its infancy, with Illinois researchers among those who are defining it.

"Our laboratory is using both animal and human models to address the extent to which exercise affects immune functioning and susceptibility to infectious disease in older populations," Woods said. "We have obtained some exciting preliminary data in mice that suggest that moderate exercise or training may boost some immune function measures and reduce mortality caused by influenza. While we don’t have corollary evidence yet in people, we are in the midst of conducting a large clinical exercise trial in older adults, funded by the National Institute on Aging, that will provide definitive evidence as to whether moderate exercise training influences immune function."

In the meantime, results of one study conducted in Woods’ lab, published in the current online edition of the journal Brain, Behavior and Immunity, indicates that exercise training increases the ratio of naïve T cells to memory T cells in the spleens of older mice. The finding is potentially significant, he said, because, on this measure, "we turn old mice into young mice." When people and animals age, he explained, the thymus, which produces naïve T lymphocytes, shrinks, thus producing fewer naïve cells. "This is one reason that older people/animals have trouble responding to new environmental pathogens."

And with the recent appearance of so many new environmental pathogens -- from West Nile Virus to SARS and monkeypox -- Woods said the ability to boost the immune systems of the elderly, who are among the populations most at risk from infection, is a worthy goal.

Melissa Mitchell | EurekAlert!
Further information:
http://www.uiuc.edu/

More articles from Health and Medicine:

nachricht Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center

nachricht Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Rainbow colors reveal cell history: Uncovering β-cell heterogeneity

22.09.2017 | Life Sciences

Penn first in world to treat patient with new radiation technology

22.09.2017 | Medical Engineering

Calculating quietness

22.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>