Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

’Disappearing’ tumour study could lead to new cancer treatments

04.06.2003


A research study at The University of Nottingham looking at how growth can contribute to spontaneous childhood cancer regression could lead to more effective ways of treating tumours.



The one-year project, led by Christopher Jones in the School of Nursing in collaboration with Dr Michael Symonds in the Division of Child Health and Dr David Walker at the University’s Children’s Brain Tumour Research Centre, will look at whether growth hormone plays a part in tumours spontaneously getting better.

The researchers are looking at neuroblastoma, which accounts for around six per cent of all childhood cancers. Around 100 children develop neuroblastoma each year in the UK and most of these are less than four years of age.


In around three-quarters of these cases the cancer spreads around the body and the current survival rates are only around 30 per cent.

However, when a tumour of this kind occurs in the liver, particularly in the first year of life, it is only fatal in between 10 and 20 per cent of sufferers and, in many cases, spontaneously regresses without the need for treatment.

Scientists have been studying this medical phenomenon for many years, although most research has centred on looking at the biology of the tumour in an effort to discover why it self-destructs.

The Nottingham researchers, however, believe it could be something within the body and not the tumour itself that sparks off this regression and think that it could be due to the release of hormones that control growth in infancy.

Dr Michael Symonds said: "We believe that spontaneous tumour regression is linked to unique changes within the liver in early childhood, which coincide with the onset of growth hormone-dependent growth."

It is hoped that the study, funded with £7,000 from the Special Trustees of Nottingham University Hospital, will attract more funding for the study of childhood cancers and could even lead to more effective treatments for non-regressing neuroblastoma, as well as other aggressive tumours such as breast cancer and certain types of childhood brain tumours.

Lyn Heath-Harvey | alfa
Further information:
http://www.nottingham.ac.uk/public-affairs/index.html

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>