Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Novel Drugs for the Treatment of Diabetes Developed by Hebrew University Researcher

30.05.2003


A new approach to providing medication for adult diabetics (type 2 diabetes) that is not dependent on insulin has been developed by a doctoral student at the Hebrew University of Jerusalem. For his work, which he did for his Ph.D. thesis in pharmacology, Arie Gruzman was awarded one of this year’s Kaye Innovation Awards at the Hebrew University.


Arie Gruzman



Unlike other conventional drugs that require active insulin-producing cells in the pancreas and that often fail to overcome a companion problem of insulin resistance, the novel compounds developed by Gruzman and his supervisor, Prof. Shlomo Sasson, in collaboration with Prof. Yehoshua Katzhendler and Prof. Erol Cerasi of the Hebrew University School of Pharmacy and the Faculty of Medicine, are unique in that they can reduce hyperglycemia (above-normal levels of glucose in the blood) by increasing the rate of glucose disposal in the blood in a non-insulin-dependent manner.

The new drugs, when fully developed, may provide a treatment to diabetic patients who have especially serious problems of insufficient natural insulin production and/or resistance to insulin.


A patent for these new compounds – which, perhaps surprisingly, are based on D-Xylose, a sugar found in fruits -- has been obtained through the Hebrew University’s Yissum Research Development Company. The laboratory work was supported financially by the Deutsch Foundation of Venezuela and the Nophar Program of the Israel Ministry of Trade and Industry.

Gruzman, 32, was born in Russia and studied at a medical institute in his home town of Nizhny Novogrod. He immigrated to Israel 12 years ago and earned a B.Sc.degree in pharmaceutical chemistry at Bar-Ilan University, after which he began his graduate studies at the Hebrew University. He is married to another immigrant from the former U.S.S.R., who is a graduate student at the Hebrew University Faculty of Medicine, and they are the parents of two daughters.

The Kaye Innovation Awards at the Hebrew University have been awarded annually since 1994. Isaac Kaye of England, a prominent industrialist in the pharmaceutical industry, established the awards to encourage faculty, staff, and students of the university to develop innovative methods and inventions with good commercial potential which have benefited or will benefit the university and society. The Kaye Innovation Awards at the Hebrew University were awarded on May 27, during the 66th meeting of the University Board of Governors.

For further information: Jerry Barach, Dept. of Media Relations, the Hebrew University, 02-5864772; Orit Sulitzeanu, spokesperson, 052-608016

Jerry Barach | Hebrew University

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>