Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Atkins diet shows surprising results, researcher says

22.05.2003


One-year study shows diet may be as effective and safe as conventional diets



A 3-center study led by researchers at the Weight and Eating Disorders Program of the University of Pennsylvania School of Medicine reports the results of the first controlled trial of the Atkins Diet. The Atkins Diet limits carbohydrates but permits unrestricted amounts of protein and fat. Compared to a conventional, high- carbohydrate, low-calorie approach, Atkins dieters lost twice as much weight at 3 and 6 months but there was no difference between the groups at 1 year. Despite the lack of differences in weight loss at 1 year, the Atkins dieters had significantly greater increases in good cholesterol (HDL) and greater decreases in triglycerides.

The study, to be published in the May 22 issue of the New England Journal of Medicine, was led by Gary Foster, Ph.D. Associate Professor of Psychiatry and Clinical Director of the Weight and Eating Disorders Program at the University of Pennsylvania. Samuel Klein, MD of Washington University in St. Louis and James Hill, Ph.D. and Holly Wyatt, M.D. of the University of Colorado were the lead investigators at the other centers. The study investigated 63 obese men and women who were 44 years of age and weighed and average of 216 pounds.


All participants met with a registered dietitian at 0, 3, 6 and 12 months. Those in the Atkins group were given a copy of Dr. Atkins New Diet Revolution and asked to follow the diet as described. The conventional diet group was given instructional materials on a 1200-1500 calories/day (women) or 1500-1800 calories /day (men) diet that consisted of 60% carbohydrate 25% fat, and 15% protein based on the Food Guide Pyramid. Atkins participants lost an average of 14.7 pounds compared with 5.8 pounds in the conventional group at 3 months, 15.2 pounds versus 6.9 pounds at 6 months, and 9.5 versus 5.4 pounds at 12 months. At 1 year, Atkins participants had greater increases in HDL cholesterol (18% vs. 3%) and greater reductions in triglycerides (-28% vs. 1%) than did those following a conventional diet. Neither group showed changes in LDL (bad) cholesterol at 1 year .

"Obesity is a national public health problem, and we need to evaluate alternative weight loss approaches aggressively. Widely recommend low carbohydrate approaches may be premature, but our initial findings suggest that such diets may not have the adverse effects that were anticipated” Foster stated. "The real issue is whether low carbohydrate approaches help patients maintain their weight loss better than conventional approaches. It will also be important to determine whether the effects of the diet on cholesterol are the same during weight maintenance as they are they are during weight loss.” Foster also cautioned.

Results of this first, randomized, controlled study of the Atkins diet suggest that low- carbohydrate diets may not be as harmful as anticipated. "Larger and longer studies are needed to assess the long-term safety and efficacy of low carbohydrate approaches in the management of obesity. These preliminary data suggest that weight losses will be comparable to conventional approaches over a 1 year period, but there may be some favorable effects of a low-carbohydrate approach in terms of triglycerides and HDL (good) cholesterol,” Foster said.

This study was funded through grants from the National Institutes of Health (NIH) General Clinical Research Centers at the University of Pennsylvania, Washington University and the University of Colorado. Others who participated in the study at Penn were Brian McGuckin Ed.M, Research Coordinator; Philippe Szapary, MD, Assistant Professor of Medicine, and Daniel Rader, MD, Associate Professor of Medicine.

Similar findings for a low-carbohydrate diet by another group of Penn faculty working at Philadelphia VA Medical Center were also reported in the May 22 issue of the New England Journal of Medicine. In their 6-month study, Frederick Samaha, MD, and colleagues found that a low carbohydrate diet was associated with greater weight losses, reductions in triglycerides and improvements in insulin sensitivity compared to low-calorie, high-carbohydrate diet in 132 patients who were 53 years old and weighed 288 pounds.

Foster and his colleagues at the Washington University and the University of Colorado are currently enrolling participants for a large, NIH-funded, 5-year study of low- and high-carbohydrate diets.

“This larger study of 360 participants will help us more fully assess the benefits and risks of low-carbohydrate diets on bone mass, kidney function, arterial function and exercise tolerance,” Foster said.

Ellen O’Brien | EurekAlert!
Further information:
http://www.med.upenn.edu/

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>