Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Atkins diet shows surprising results, researcher says

22.05.2003


One-year study shows diet may be as effective and safe as conventional diets



A 3-center study led by researchers at the Weight and Eating Disorders Program of the University of Pennsylvania School of Medicine reports the results of the first controlled trial of the Atkins Diet. The Atkins Diet limits carbohydrates but permits unrestricted amounts of protein and fat. Compared to a conventional, high- carbohydrate, low-calorie approach, Atkins dieters lost twice as much weight at 3 and 6 months but there was no difference between the groups at 1 year. Despite the lack of differences in weight loss at 1 year, the Atkins dieters had significantly greater increases in good cholesterol (HDL) and greater decreases in triglycerides.

The study, to be published in the May 22 issue of the New England Journal of Medicine, was led by Gary Foster, Ph.D. Associate Professor of Psychiatry and Clinical Director of the Weight and Eating Disorders Program at the University of Pennsylvania. Samuel Klein, MD of Washington University in St. Louis and James Hill, Ph.D. and Holly Wyatt, M.D. of the University of Colorado were the lead investigators at the other centers. The study investigated 63 obese men and women who were 44 years of age and weighed and average of 216 pounds.


All participants met with a registered dietitian at 0, 3, 6 and 12 months. Those in the Atkins group were given a copy of Dr. Atkins New Diet Revolution and asked to follow the diet as described. The conventional diet group was given instructional materials on a 1200-1500 calories/day (women) or 1500-1800 calories /day (men) diet that consisted of 60% carbohydrate 25% fat, and 15% protein based on the Food Guide Pyramid. Atkins participants lost an average of 14.7 pounds compared with 5.8 pounds in the conventional group at 3 months, 15.2 pounds versus 6.9 pounds at 6 months, and 9.5 versus 5.4 pounds at 12 months. At 1 year, Atkins participants had greater increases in HDL cholesterol (18% vs. 3%) and greater reductions in triglycerides (-28% vs. 1%) than did those following a conventional diet. Neither group showed changes in LDL (bad) cholesterol at 1 year .

"Obesity is a national public health problem, and we need to evaluate alternative weight loss approaches aggressively. Widely recommend low carbohydrate approaches may be premature, but our initial findings suggest that such diets may not have the adverse effects that were anticipated” Foster stated. "The real issue is whether low carbohydrate approaches help patients maintain their weight loss better than conventional approaches. It will also be important to determine whether the effects of the diet on cholesterol are the same during weight maintenance as they are they are during weight loss.” Foster also cautioned.

Results of this first, randomized, controlled study of the Atkins diet suggest that low- carbohydrate diets may not be as harmful as anticipated. "Larger and longer studies are needed to assess the long-term safety and efficacy of low carbohydrate approaches in the management of obesity. These preliminary data suggest that weight losses will be comparable to conventional approaches over a 1 year period, but there may be some favorable effects of a low-carbohydrate approach in terms of triglycerides and HDL (good) cholesterol,” Foster said.

This study was funded through grants from the National Institutes of Health (NIH) General Clinical Research Centers at the University of Pennsylvania, Washington University and the University of Colorado. Others who participated in the study at Penn were Brian McGuckin Ed.M, Research Coordinator; Philippe Szapary, MD, Assistant Professor of Medicine, and Daniel Rader, MD, Associate Professor of Medicine.

Similar findings for a low-carbohydrate diet by another group of Penn faculty working at Philadelphia VA Medical Center were also reported in the May 22 issue of the New England Journal of Medicine. In their 6-month study, Frederick Samaha, MD, and colleagues found that a low carbohydrate diet was associated with greater weight losses, reductions in triglycerides and improvements in insulin sensitivity compared to low-calorie, high-carbohydrate diet in 132 patients who were 53 years old and weighed 288 pounds.

Foster and his colleagues at the Washington University and the University of Colorado are currently enrolling participants for a large, NIH-funded, 5-year study of low- and high-carbohydrate diets.

“This larger study of 360 participants will help us more fully assess the benefits and risks of low-carbohydrate diets on bone mass, kidney function, arterial function and exercise tolerance,” Foster said.

Ellen O’Brien | EurekAlert!
Further information:
http://www.med.upenn.edu/

More articles from Health and Medicine:

nachricht Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University

nachricht Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>