USC researchers find ways to improve effectiveness against tumors
Researchers from the Keck School of Medicine of the University of Southern California have isolated a protein fragment derived from the cancer immunotherapy drug interleukin 2 (IL-2) that seems to enhance the uptake of chemotherapeutic agents into tumors.
In fact, says Alan Epstein, M.D., Ph.D., professor of pathology at the Keck School of Medicine, when this patented protein fragment is attached to a tumor-targeting antibody, it can prompt tumors to soak up more than 300 percent the normal amount of chemotherapy drugs. It does this, Epstein says, by making the tumors blood vessel walls more "open" or permeable to the drugs. (Blood vessel walls are made of epithelial cells that are usually tightly joined together; when the junctions between those cells loosen up, it becomes easier for molecules to enter or leave the bloodstream.)
Jon Weiner | EurekAlert!
Plasmonic biosensors enable development of new easy-to-use health tests
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ASU scientists develop new, rapid pipeline for antimicrobials
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MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
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