Non-steroidal anti-inflammatory drugs (NSAIDs) may damage more of the intestine than previously thought, according to images taken by a swallowable, capsule-size camera pill used in a Baylor College of Medicine study.
According to the study, announced today at the Digestive Disease Week 2003 conference in Orlando, capsule endoscopy detected NSAIDs-related injury in the small bowel, an area of the gastrointestinal tract unreachable by other diagnostic tools such as endoscopes. The tool detected small bowel erosions in 62 percent of NSAID users compared to 5 percent of non-NSAID users.
"More than 100 million prescriptions for NSAIDS are written annually in the United States," said Dr. David Graham, lead author of the study and a professor of medicine and molecular virology at Baylor in Houston and chief of the gastroenterology section of Houston VA Medical Center. "The study shows that the patients who take NSAIDs regularly have an increased risk of small intestinal mucosal ulceration and bleeding."
Anissa Anderson Orr | EurekAlert!
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