A new anti-herpes agent derived from a common herb effectively treats and prevents the disease in animals. Researchers from Dalhousie University in Nova Scotia present their data today at the 103rd General Meeting of the American Society for Microbiology.
"Prunella vulgaris [also known as self-heal] is a perennial plant commonly found in China, the British Isles, Europe, and North America. In herbal literature, P. vulgaris has been described as a hot water infusion to treat sores in the mouth and throat, as an astringent for internal and external purposes, as a crude anti-cancer drug, and as a herbal remedy to lower high blood pressure," says Song Lee, one of the researchers on the study.
Lee and his colleagues extracted a lignin-carbohydrate compound from the plant, which was incorporated into a topical cream and tested on mice and guinea pigs with experimental herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2) infections. Guinea pigs receiving the lignin-carbohydrate complex cream treatment showed a significant reduction in skin lesions compared to those that received no treatment. Mice receiving the lignin-carbohydrate complex cream treatment showed a significant increase in survival rate compared to animals that received no treatment.
Jim Sliwa | EurekAlert!
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