Finding new ways to deliver gene therapy without using viruses as carriers is the aim of research by chemist Michael Nantz at UC Davis.
Nantzs lab engineers lipids, oily molecules that can form a protective complex around DNA, to do the same job as a virus. The lipids protect the DNA and help it get into the target cell. The approach could eventually make gene therapy treatments that are stable enough to take as a pill.
Gene therapy holds the promise of curing diseases such as diabetes, cystic fibrosis or Parkinsons disease by replacing damaged or missing genes. To do that, a new piece of DNA has to be carried into cells in the right part of the body.
Andy Fell | EurekAlert!
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