Because they are able to recognize a particular cell marker — a protein — antibodies are generally used to identify abnormal cells in the body. As such, they play a key role in diagnosis, treatment and basic research.
At the Institut Curie, CNRS research scientists have recently prepared a new type of antibody which for the first time combines several crucial features: it can be produced in a few days, it can be expressed directly in cells, and it is, moreover, sensitive to the shape of proteins. The latter property is particularly important as the activity of proteins depends on their shape. Thus certain cancers or illnesses such as Creutzfeldt-Jakob disease are due to a protein that has assumed an abnormal shape.
This study, which constitutes a technological advance both for basic research and diagnosis, is published in the 9 May 2003 issue of Science.
All stages in the life of a cell are controlled by the activity of proteins. Proteins enable cells to produce energy, to reproduce and to interact with their environment. All these processes must be closely monitored to avoid pathological dysfunction.
Catherine Goupillon | alfa
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Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
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The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
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Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
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