Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Extreme heat effective in treating some kidney cancers

08.05.2003


Image-guided radiofrequency ablation -- using heat to destroy cancers -- can preserve kidney function and avoid kidney dialysis for patients with solid renal tumors who are not surgical candidates, a new study indicates.



“We have been able to successfully destroy 50 out of 51 renal tumors in 32 patients,” says Michael Farrell, MD, consultant radiologist at Mayo Clinic in Rochester, MN, and the lead author of the study.

The easiest tumors to treat with radiofrequency ablation are those that are “growing on the outer surface of the kidney because surrounding fat insulates the tumor and insures the necessary temperatures can be acquired in order to achieve tumor cell destruction,” says Dr. Farrell. Centrally located tumors are more difficult to successfully treat, he says.


“We have followed the patients for between 1 and 27 months, and none of them have had cancer recurrence on imaging,” says Dr. Farrell. “We can potentially re-treat patients with radiofrequency ablation if their cancer returns,” he adds.

“The success rate is encouraging, but our follow-up time is relatively short. “This is not an alternative to definite surgical resection, but is an option for patients with decreased renal function, including those who’ve had a prior nephrectomy,” Dr. Farrell says. “Our aim would be to preserve renal function and avoid dialysis.” It is also an option for patients with coexisting medical morbidities which make them unsuitable for surgery, he says.

There is a low incidence of side effects in treatment, adds Dr. Farrell. Minor complications (in four patients) included pain, development of small fluid collection, and bleeding, all of which resolved themselves, he says. Major complications (in two patients) included damage to a small artery, which in turn destroyed a small area in the kidney, and heat damage to a nerve which has led to chronic, but gradually resolving, pain in the patient.

“We are seeing an increase in the number of renal tumors, especially in elderly patients. New imaging methods are detecting them incidentally, that is, patients are coming in for a radiologic examination for another reason, and the renal tumor is being found,” says Dr. Farrell. Ablation is a treatment option for these patients if they are not surgical candidates or have poor renal function, he says.


Dr. Farrell will present his study on May 8 during the American Roentgen Ray Society Annual Meeting in San Diego.

Contact: Keri J. Sperry (703) 858-4306
Danica Laub (703) 858-4332
Press Room: (619) 525-6536 (May 5-8)

Keri Sperry | EurekAlert!
Further information:
http://www.arrs.org/

More articles from Health and Medicine:

nachricht Finnish research group discovers a new immune system regulator
23.02.2018 | University of Turku

nachricht Minimising risks of transplants
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Attoseconds break into atomic interior

A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.

In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...

Im Focus: Good vibrations feel the force

A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.

By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...

Im Focus: Developing reliable quantum computers

International research team makes important step on the path to solving certification problems

Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Basque researchers turn light upside down

23.02.2018 | Physics and Astronomy

Finnish research group discovers a new immune system regulator

23.02.2018 | Health and Medicine

Attoseconds break into atomic interior

23.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>