Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sesame oil helps reduce dose of blood pressure-lowering medicine

29.04.2003


Cooking with sesame oil in place of other edible oils appears to help reduce high blood pressure and lower the amount of medication needed to control hypertension, researchers reported today at the XVth Scientific Meeting of the Inter-American Society of Hypertension. The meeting is co-sponsored by the American Heart Association’s Council for High Blood Pressure Research.



Using sesame oil as the sole cooking oil for 60 days along with drug treatment lowered patients’ blood pressure levels from 166 millimeters of mercury (mm Hg) systolic pressure (the top number in a blood pressure reading) to 134 mm Hg, and from 101 mm Hg diastolic (the lower number) to 84.6 mm Hg.

The researchers also report that the dose of nifedipine, a calcium channel blocker, was reduced from 22.7 mg per day to 7.45 mg per day by the end of the study.


"The affect of the oil on blood pressure may be due to polyunsaturated fatty acids (PUFA), and the compound sesamin – a lignan present in sesame oil. Both compounds have been shown to reduce blood pressure in hypertensive rats. Sesame lignans also inhibit the synthesis and absorption of cholesterol in these rats," says primary author Devarajan Sankar, D.O., Ph.D., a research scholar at Annamalai University, Chidambaram, Tamil Nadu, India.

Sesame oil contains 43 percent polyunsaturated fatty acids and 40 milligrams (mg) of vitamin E per 100 grams, according to the researcher. The research team has previously reported that sesame oil helps reduce blood pressure in hypertensive patients taking diuretics or beta blockers, and that sesame oil helped people with diabetes regardless of high blood pressure. Their current study tested the effect of sesame oil on people with hypertension who were already taking the calcium channel blocker drug nifedipine. Calcium channel blockers lower blood pressure by relaxing the arterial membranes.

Researchers identified 328 patients (195 men, 133 women, average age 58) who were taking 10-30 mg of nifedipine a day. They had moderate to severe long-term hypertension but no history of heart disease or stroke. Their average blood pressure was 166/101 mm Hg, which is considered stage 2 hypertension. Participants consumed an average of 35 grams of oil per day for 60 days. Researchers measured blood pressure at baseline, every 15 days and on day 60.

"Overall, we’ve added to the growing body of knowledge that suggests regular consumption of sesame oil as the sole edible oil is beneficial in many ways, including blood pressure reduction," Sankar says. However, patients should always seek advice from their physician if they have questions about their high blood pressure treatment.

Co-authors are K.V. Pugalendi, Ph.D.; G. Sambandam, M.B.B.S.; and M. Ramakrishna Rao, M.D. The meeting is also sponsored by the Inter-American Society for Hypertension and the National Heart, Lung, and Blood Institute.


CONTACT:
Carole Bullock: (214) 706-1279
Julie Del Barto (broadcast): (214) 706-1330

Carole Bullock | EurekAlert!
Further information:
http://www.americanheart.org/

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>