Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sesame oil helps reduce dose of blood pressure-lowering medicine

29.04.2003


Cooking with sesame oil in place of other edible oils appears to help reduce high blood pressure and lower the amount of medication needed to control hypertension, researchers reported today at the XVth Scientific Meeting of the Inter-American Society of Hypertension. The meeting is co-sponsored by the American Heart Association’s Council for High Blood Pressure Research.



Using sesame oil as the sole cooking oil for 60 days along with drug treatment lowered patients’ blood pressure levels from 166 millimeters of mercury (mm Hg) systolic pressure (the top number in a blood pressure reading) to 134 mm Hg, and from 101 mm Hg diastolic (the lower number) to 84.6 mm Hg.

The researchers also report that the dose of nifedipine, a calcium channel blocker, was reduced from 22.7 mg per day to 7.45 mg per day by the end of the study.


"The affect of the oil on blood pressure may be due to polyunsaturated fatty acids (PUFA), and the compound sesamin – a lignan present in sesame oil. Both compounds have been shown to reduce blood pressure in hypertensive rats. Sesame lignans also inhibit the synthesis and absorption of cholesterol in these rats," says primary author Devarajan Sankar, D.O., Ph.D., a research scholar at Annamalai University, Chidambaram, Tamil Nadu, India.

Sesame oil contains 43 percent polyunsaturated fatty acids and 40 milligrams (mg) of vitamin E per 100 grams, according to the researcher. The research team has previously reported that sesame oil helps reduce blood pressure in hypertensive patients taking diuretics or beta blockers, and that sesame oil helped people with diabetes regardless of high blood pressure. Their current study tested the effect of sesame oil on people with hypertension who were already taking the calcium channel blocker drug nifedipine. Calcium channel blockers lower blood pressure by relaxing the arterial membranes.

Researchers identified 328 patients (195 men, 133 women, average age 58) who were taking 10-30 mg of nifedipine a day. They had moderate to severe long-term hypertension but no history of heart disease or stroke. Their average blood pressure was 166/101 mm Hg, which is considered stage 2 hypertension. Participants consumed an average of 35 grams of oil per day for 60 days. Researchers measured blood pressure at baseline, every 15 days and on day 60.

"Overall, we’ve added to the growing body of knowledge that suggests regular consumption of sesame oil as the sole edible oil is beneficial in many ways, including blood pressure reduction," Sankar says. However, patients should always seek advice from their physician if they have questions about their high blood pressure treatment.

Co-authors are K.V. Pugalendi, Ph.D.; G. Sambandam, M.B.B.S.; and M. Ramakrishna Rao, M.D. The meeting is also sponsored by the Inter-American Society for Hypertension and the National Heart, Lung, and Blood Institute.


CONTACT:
Carole Bullock: (214) 706-1279
Julie Del Barto (broadcast): (214) 706-1330

Carole Bullock | EurekAlert!
Further information:
http://www.americanheart.org/

More articles from Health and Medicine:

nachricht 'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS

nachricht New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

Im Focus: Autonomous 3D scanner supports individual manufacturing processes

Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).

Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Fingerprints of quantum entanglement

16.02.2018 | Information Technology

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers

16.02.2018 | Health and Medicine

Hubble sees Neptune's mysterious shrinking storm

16.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>