Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sesame oil helps reduce dose of blood pressure-lowering medicine

29.04.2003


Cooking with sesame oil in place of other edible oils appears to help reduce high blood pressure and lower the amount of medication needed to control hypertension, researchers reported today at the XVth Scientific Meeting of the Inter-American Society of Hypertension. The meeting is co-sponsored by the American Heart Association’s Council for High Blood Pressure Research.



Using sesame oil as the sole cooking oil for 60 days along with drug treatment lowered patients’ blood pressure levels from 166 millimeters of mercury (mm Hg) systolic pressure (the top number in a blood pressure reading) to 134 mm Hg, and from 101 mm Hg diastolic (the lower number) to 84.6 mm Hg.

The researchers also report that the dose of nifedipine, a calcium channel blocker, was reduced from 22.7 mg per day to 7.45 mg per day by the end of the study.


"The affect of the oil on blood pressure may be due to polyunsaturated fatty acids (PUFA), and the compound sesamin – a lignan present in sesame oil. Both compounds have been shown to reduce blood pressure in hypertensive rats. Sesame lignans also inhibit the synthesis and absorption of cholesterol in these rats," says primary author Devarajan Sankar, D.O., Ph.D., a research scholar at Annamalai University, Chidambaram, Tamil Nadu, India.

Sesame oil contains 43 percent polyunsaturated fatty acids and 40 milligrams (mg) of vitamin E per 100 grams, according to the researcher. The research team has previously reported that sesame oil helps reduce blood pressure in hypertensive patients taking diuretics or beta blockers, and that sesame oil helped people with diabetes regardless of high blood pressure. Their current study tested the effect of sesame oil on people with hypertension who were already taking the calcium channel blocker drug nifedipine. Calcium channel blockers lower blood pressure by relaxing the arterial membranes.

Researchers identified 328 patients (195 men, 133 women, average age 58) who were taking 10-30 mg of nifedipine a day. They had moderate to severe long-term hypertension but no history of heart disease or stroke. Their average blood pressure was 166/101 mm Hg, which is considered stage 2 hypertension. Participants consumed an average of 35 grams of oil per day for 60 days. Researchers measured blood pressure at baseline, every 15 days and on day 60.

"Overall, we’ve added to the growing body of knowledge that suggests regular consumption of sesame oil as the sole edible oil is beneficial in many ways, including blood pressure reduction," Sankar says. However, patients should always seek advice from their physician if they have questions about their high blood pressure treatment.

Co-authors are K.V. Pugalendi, Ph.D.; G. Sambandam, M.B.B.S.; and M. Ramakrishna Rao, M.D. The meeting is also sponsored by the Inter-American Society for Hypertension and the National Heart, Lung, and Blood Institute.


CONTACT:
Carole Bullock: (214) 706-1279
Julie Del Barto (broadcast): (214) 706-1330

Carole Bullock | EurekAlert!
Further information:
http://www.americanheart.org/

More articles from Health and Medicine:

nachricht New malaria analysis method reveals disease severity in minutes
14.08.2017 | University of British Columbia

nachricht New type of blood cells work as indicators of autoimmunity
14.08.2017 | Instituto de Medicina Molecular

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

New bioimaging technique is fast and economical

21.08.2017 | Medical Engineering

Silk could improve sensitivity, flexibility of wearable body sensors

21.08.2017 | Materials Sciences

On the way to developing a new active ingredient against chronic infections

21.08.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>