Johns Hopkins researchers have developed an inexpensive, reliable way to make large quantities of targeted immune cells that one day may provide a life-saving defense against cancers and viral infections.
Using artificial antigen presenting cells, or aAPCs, the scientists converted run-of-the-mill immune cells into a horde of specific, targeted invader-fighting machines, they report in the advance online version of Nature Medicine on April 21.
"The ability to make vast quantities of targeted, antigen-specific immune cells in the lab broadens their potential in tackling a wide array of diseases, especially cancers," says Jonathan Schneck, Ph.D., professor of pathology and medicine at the Johns Hopkins School of Medicine. "Our technique provides an off-the-shelf way to create these cells."
Joanna Downer | EurekAlert!
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