Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Retinal abnormalities and AMD associated with hypertension and pulse pressure

10.04.2003


Retinal abnormalities in older people without diabetes are related to hypertension. Higher blood and pulse pressure are also associated with an increased incidence of macular abnormalities, including wet and dry age-related macular degeneration (AMD). These are the major findings of two studies appearing in the April issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, the Eye M.D. Association.



The first study, assessing more than 2,000 men and women without diabetes, found retinal abnormalities in older people who do not have diabetes are related to high blood pressure, and retinopathy is associated with coronary heart disease, stroke, and carotid artery thickening. However, these conditions are distinct from atherosclerosis, a common form of hardening of the arteries.

According to Tien Yin Wong, FRCSE, MD, PhD, lead author of the Cardiovascular Health Study, "These changes may be markers for blood and small-vessel diseases of the brain, and have been shown to predict stroke independently of standard risk factors. Thus, patients with these changes may benefit from a full cardiovascular assessment." Dr. Wong is assistant professor at National University of Singapore and visiting assistant professor at University of Wisconsin-Madison.


The second study, part of the Beaver Dam Eye Study, found higher systolic blood pressure – the higher pressure when the heart contracts – was associated with the 10-year incidence of loss or degeneration of pigment cells that nourish the retina’s visual cells and with wet age-related macular degeneration. It also found higher pulse pressure, the difference between the higher (systolic) and lower (diastolic) blood pressure, was associated with progression of age-related macular degeneration with loss of retinal pigment cells, release of pigment into the rest of the retina, and the development of wet age-related macular degeneration.

Ronald Klein, MD, MPH, lead author of this study and professor of ophthalmology at the University of Wisconsin-Madison, explained, "Though this study shows that hypertension is associated with the development of advanced age-related macular degeneration, there is a need for further study to see whether the tight control of blood pressure will reduce the incidence of this form of retinal disease."

Academy spokesperson Paul Sternberg, Jr., MD, professor and chairman of the Department of Ophthalmology and Visual Sciences at Vanderbilt University, said, "These studies show that the eye provides a window to visualize blood vessel abnormalities directly, allowing us to identify patients who are at higher risk for vascular diseases affecting the coronary, carotid, and cerebrovascular arteries."


###
The first study was supported by a grant from the National Heart, Lung and Blood Institute, National Institutes of Health, and the second study was supported by grants from the National Institutes of Health and from Research to Prevent Blindness.

The American Academy of Ophthalmology is the world’s largest association of eye physicians and surgeons--Eye M.D.s--with more than 27,000 members worldwide. For more information about eye health care, visit the Academy’s partner Web site, the Medem Network, at www.medem.com/eyemd. To find an Eye M.D. in your area, visit the Academy’s Web site at www.aao.org.

Peter Greene | EurekAlert!
Further information:
http://www.medem.com/eyemd
http://www.aao.org

More articles from Health and Medicine:

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht On track to heal leukaemia
18.01.2017 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

New Study Will Help Find the Best Locations for Thermal Power Stations in Iceland

19.01.2017 | Earth Sciences

Not of Divided Mind

19.01.2017 | Life Sciences

Molecule flash mob

19.01.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>