Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Retinal abnormalities and AMD associated with hypertension and pulse pressure

10.04.2003


Retinal abnormalities in older people without diabetes are related to hypertension. Higher blood and pulse pressure are also associated with an increased incidence of macular abnormalities, including wet and dry age-related macular degeneration (AMD). These are the major findings of two studies appearing in the April issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, the Eye M.D. Association.



The first study, assessing more than 2,000 men and women without diabetes, found retinal abnormalities in older people who do not have diabetes are related to high blood pressure, and retinopathy is associated with coronary heart disease, stroke, and carotid artery thickening. However, these conditions are distinct from atherosclerosis, a common form of hardening of the arteries.

According to Tien Yin Wong, FRCSE, MD, PhD, lead author of the Cardiovascular Health Study, "These changes may be markers for blood and small-vessel diseases of the brain, and have been shown to predict stroke independently of standard risk factors. Thus, patients with these changes may benefit from a full cardiovascular assessment." Dr. Wong is assistant professor at National University of Singapore and visiting assistant professor at University of Wisconsin-Madison.


The second study, part of the Beaver Dam Eye Study, found higher systolic blood pressure – the higher pressure when the heart contracts – was associated with the 10-year incidence of loss or degeneration of pigment cells that nourish the retina’s visual cells and with wet age-related macular degeneration. It also found higher pulse pressure, the difference between the higher (systolic) and lower (diastolic) blood pressure, was associated with progression of age-related macular degeneration with loss of retinal pigment cells, release of pigment into the rest of the retina, and the development of wet age-related macular degeneration.

Ronald Klein, MD, MPH, lead author of this study and professor of ophthalmology at the University of Wisconsin-Madison, explained, "Though this study shows that hypertension is associated with the development of advanced age-related macular degeneration, there is a need for further study to see whether the tight control of blood pressure will reduce the incidence of this form of retinal disease."

Academy spokesperson Paul Sternberg, Jr., MD, professor and chairman of the Department of Ophthalmology and Visual Sciences at Vanderbilt University, said, "These studies show that the eye provides a window to visualize blood vessel abnormalities directly, allowing us to identify patients who are at higher risk for vascular diseases affecting the coronary, carotid, and cerebrovascular arteries."


###
The first study was supported by a grant from the National Heart, Lung and Blood Institute, National Institutes of Health, and the second study was supported by grants from the National Institutes of Health and from Research to Prevent Blindness.

The American Academy of Ophthalmology is the world’s largest association of eye physicians and surgeons--Eye M.D.s--with more than 27,000 members worldwide. For more information about eye health care, visit the Academy’s partner Web site, the Medem Network, at www.medem.com/eyemd. To find an Eye M.D. in your area, visit the Academy’s Web site at www.aao.org.

Peter Greene | EurekAlert!
Further information:
http://www.medem.com/eyemd
http://www.aao.org

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Electrode materials from the microwave oven

19.10.2017 | Materials Sciences

New material for digital memories of the future

19.10.2017 | Materials Sciences

Physics boosts artificial intelligence methods

19.10.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>