Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Retinal abnormalities and AMD associated with hypertension and pulse pressure

10.04.2003


Retinal abnormalities in older people without diabetes are related to hypertension. Higher blood and pulse pressure are also associated with an increased incidence of macular abnormalities, including wet and dry age-related macular degeneration (AMD). These are the major findings of two studies appearing in the April issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, the Eye M.D. Association.



The first study, assessing more than 2,000 men and women without diabetes, found retinal abnormalities in older people who do not have diabetes are related to high blood pressure, and retinopathy is associated with coronary heart disease, stroke, and carotid artery thickening. However, these conditions are distinct from atherosclerosis, a common form of hardening of the arteries.

According to Tien Yin Wong, FRCSE, MD, PhD, lead author of the Cardiovascular Health Study, "These changes may be markers for blood and small-vessel diseases of the brain, and have been shown to predict stroke independently of standard risk factors. Thus, patients with these changes may benefit from a full cardiovascular assessment." Dr. Wong is assistant professor at National University of Singapore and visiting assistant professor at University of Wisconsin-Madison.


The second study, part of the Beaver Dam Eye Study, found higher systolic blood pressure – the higher pressure when the heart contracts – was associated with the 10-year incidence of loss or degeneration of pigment cells that nourish the retina’s visual cells and with wet age-related macular degeneration. It also found higher pulse pressure, the difference between the higher (systolic) and lower (diastolic) blood pressure, was associated with progression of age-related macular degeneration with loss of retinal pigment cells, release of pigment into the rest of the retina, and the development of wet age-related macular degeneration.

Ronald Klein, MD, MPH, lead author of this study and professor of ophthalmology at the University of Wisconsin-Madison, explained, "Though this study shows that hypertension is associated with the development of advanced age-related macular degeneration, there is a need for further study to see whether the tight control of blood pressure will reduce the incidence of this form of retinal disease."

Academy spokesperson Paul Sternberg, Jr., MD, professor and chairman of the Department of Ophthalmology and Visual Sciences at Vanderbilt University, said, "These studies show that the eye provides a window to visualize blood vessel abnormalities directly, allowing us to identify patients who are at higher risk for vascular diseases affecting the coronary, carotid, and cerebrovascular arteries."


###
The first study was supported by a grant from the National Heart, Lung and Blood Institute, National Institutes of Health, and the second study was supported by grants from the National Institutes of Health and from Research to Prevent Blindness.

The American Academy of Ophthalmology is the world’s largest association of eye physicians and surgeons--Eye M.D.s--with more than 27,000 members worldwide. For more information about eye health care, visit the Academy’s partner Web site, the Medem Network, at www.medem.com/eyemd. To find an Eye M.D. in your area, visit the Academy’s Web site at www.aao.org.

Peter Greene | EurekAlert!
Further information:
http://www.medem.com/eyemd
http://www.aao.org

More articles from Health and Medicine:

nachricht World first: Massive thrombosis removed during early pregnancy
20.07.2017 | Universitätsspital Bern

nachricht Therapy of preterm birth in sight?
19.07.2017 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

Leipzig HTP-Forum discusses "hydrothermal processes" as a key technology for a biobased economy

12.07.2017 | Event News

 
Latest News

Researchers create new technique for manipulating polarization of terahertz radiation

20.07.2017 | Information Technology

High-tech sensing illuminates concrete stress testing

20.07.2017 | Materials Sciences

First direct observation and measurement of ultra-fast moving vortices in superconductors

20.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>