Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Retinal abnormalities and AMD associated with hypertension and pulse pressure

10.04.2003


Retinal abnormalities in older people without diabetes are related to hypertension. Higher blood and pulse pressure are also associated with an increased incidence of macular abnormalities, including wet and dry age-related macular degeneration (AMD). These are the major findings of two studies appearing in the April issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, the Eye M.D. Association.



The first study, assessing more than 2,000 men and women without diabetes, found retinal abnormalities in older people who do not have diabetes are related to high blood pressure, and retinopathy is associated with coronary heart disease, stroke, and carotid artery thickening. However, these conditions are distinct from atherosclerosis, a common form of hardening of the arteries.

According to Tien Yin Wong, FRCSE, MD, PhD, lead author of the Cardiovascular Health Study, "These changes may be markers for blood and small-vessel diseases of the brain, and have been shown to predict stroke independently of standard risk factors. Thus, patients with these changes may benefit from a full cardiovascular assessment." Dr. Wong is assistant professor at National University of Singapore and visiting assistant professor at University of Wisconsin-Madison.


The second study, part of the Beaver Dam Eye Study, found higher systolic blood pressure – the higher pressure when the heart contracts – was associated with the 10-year incidence of loss or degeneration of pigment cells that nourish the retina’s visual cells and with wet age-related macular degeneration. It also found higher pulse pressure, the difference between the higher (systolic) and lower (diastolic) blood pressure, was associated with progression of age-related macular degeneration with loss of retinal pigment cells, release of pigment into the rest of the retina, and the development of wet age-related macular degeneration.

Ronald Klein, MD, MPH, lead author of this study and professor of ophthalmology at the University of Wisconsin-Madison, explained, "Though this study shows that hypertension is associated with the development of advanced age-related macular degeneration, there is a need for further study to see whether the tight control of blood pressure will reduce the incidence of this form of retinal disease."

Academy spokesperson Paul Sternberg, Jr., MD, professor and chairman of the Department of Ophthalmology and Visual Sciences at Vanderbilt University, said, "These studies show that the eye provides a window to visualize blood vessel abnormalities directly, allowing us to identify patients who are at higher risk for vascular diseases affecting the coronary, carotid, and cerebrovascular arteries."


###
The first study was supported by a grant from the National Heart, Lung and Blood Institute, National Institutes of Health, and the second study was supported by grants from the National Institutes of Health and from Research to Prevent Blindness.

The American Academy of Ophthalmology is the world’s largest association of eye physicians and surgeons--Eye M.D.s--with more than 27,000 members worldwide. For more information about eye health care, visit the Academy’s partner Web site, the Medem Network, at www.medem.com/eyemd. To find an Eye M.D. in your area, visit the Academy’s Web site at www.aao.org.

Peter Greene | EurekAlert!
Further information:
http://www.medem.com/eyemd
http://www.aao.org

More articles from Health and Medicine:

nachricht Cholesterol-lowering drugs may fight infectious disease
22.08.2017 | Duke University

nachricht Once invincible superbug squashed by 'superteam' of antibiotics
22.08.2017 | University at Buffalo

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

What the world's tiniest 'monster truck' reveals

23.08.2017 | Life Sciences

Treating arthritis with algae

23.08.2017 | Life Sciences

Witnessing turbulent motion in the atmosphere of a distant star

23.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>