The drug ramipril significantly reduced the onset of debilitating and often-fatal heart failure in a large group of high-risk patients, researchers report in todays rapid access issue of Circulation: Journal of the American Heart Association.
Ramipril, trade-named Altace, is one of a family of high blood pressure medications known as ACE inhibitors. The drugs reduce the risk of death from heart failure – the inability of a weakened or damaged heart to pump enough blood through the body – in people who suffer heart attacks. The American Heart Association estimates that nearly 5 million people in the United States have congestive heart failure.
"This trial extends the benefits of ACE inhibitors beyond what has been previously proven," says lead author Malcolm Arnold, M.D., "It shows, for the first time, that heart failure can be prevented in a broad range of high risk patients."
Carole Bullock | EurekAlert!
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