Parents concerned about use of oral steroids to treat their asthmatic children will be reassured by a new study conducted by a team of clinicians at the Research Institute of the McGill University Health Centre (MUHC) and the Shriners Hospital (Montreal). This study, the first to evaluate the effects of short courses of oral steroids on bone density and hormone function, was published in the February issue of the international journal Pediatrics.
“Often parents will be hesitant to administer prescribed oral glucocorticoids, a subset of steroids, to their asthmatic children because they are worried about the potential side effects,” says Dr. Francine Ducharme, pediatrician at the Montreal Children’s Hospital of the MUHC and lead author of the study. “These drugs are extremely effective at reducing inflammation of the airways and treating asthma flare-ups. This study shows that parents do not need to be concerned when these drugs are used for up to five days to treat acute asthma exacerbations.”
“One of the main concerns with glucocorticoid use is their effect on bones,” says Dr. Gilles Chabot, pediatrician at the Shriners Hospital and coauthor of the study. “We were able to look directly at the children’s bones and determine that the repeated short courses of oral glucocorticoids had no detectable cumulative negative effect on bone formation.”
Christine Zeindler | EurekAlert!
Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital
Highly precise wiring in the Cerebral Cortex
21.09.2017 | Max-Planck-Institut für Hirnforschung
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
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21.09.2017 | Health and Medicine