Researchers in Oxford University’s Inorganic Chemistry Laboratory have found that they can intercalate a range of pharmaceutically active molecules between the layers of a layered inorganic host.
While working on the ion-exchange abilities of a family of inorganic materials known as Layered Double Hydroxides (LDHs), researchers have recognised that many commonly prescribed drugs and other over-the-counter medicines are either anions or can be conveniently and reversibly converted into an anion form. Research revealed that addition of one of these LDHs to a solution of a chosen pharmaceutical in water at room temperature results in intercalation of the these molecules between the sheets of the host structure. The LDHs are able to swell by up to 20Å to accommodate the size of the new guest molecules.
Certain drugs require controlled release and/or amelioration of side effects. LDHs already have medicinal properties in their own right as antacid and antipepsin agents. Propriety antacids products such as Talcid™ and Altacite™ contain the LDH [Mg6Al2(OH)16]CO3.
Jennifer Johnson | alfa
'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS
New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
20.02.2018 | Life Sciences
20.02.2018 | Life Sciences
20.02.2018 | Physics and Astronomy