Researchers in the Baxter Laboratory at Stanford University Medical Center have published new evidence showing that cells from the bone marrow might help repair or maintain cells in other tissues. In a paper in this weeks online edition of the Proceedings of the National Academy of Sciences, the researchers describe finding chromosomes from a bone marrow transplant in the brain cells of transplant recipients.
When people receive a bone marrow transplant after high-dose chemotherapy, some of the transplanted cells regenerate the blood-making cells that were destroyed. In past experiments in mice, Helen Blau, PhD, the Donald E. and Delia B. Baxter Professor of Pharmacology at the School of Medicine, found that cells from the transplant could also relocate to tissues throughout the body rather than being restricted to the bone marrow and blood.
"Now we know that it can also happen in humans," said James Weimann, PhD, first author on the paper and a senior research scientist in Blaus lab.
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