Researchers at Washington University School of Medicine in St. Louis have found that immune cells called B cells and the antibodies they produce play a critical early role in defending the body against West Nile Virus. The results are published in the February issue of the Journal of Virology.
Mice that lacked B cells and antibodies were completely unable to combat the virus. They developed serious brain and spinal-cord infection and ultimately died.
"These findings may help explain why the elderly and others with weakened immunity are most likely to develop serious disease when infected by the virus," says study leader Michael S. Diamond, M.D., Ph.D., assistant professor of medicine, of molecular microbiology and of pathology and immunology.
Darrell Ward | EurekAlert!
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Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
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15.12.2017 | Life Sciences
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