Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Early Promise Of New Treatment To Reduce Infection Associated With Chemotherapy

24.01.2003


Authors of a fast-track study in this week’s issue of THE LANCET propose an alternative to antibiotics to treat infection associated with the use of chemotherapy for patients with blood cancer.



The toxic effects of chemotherapy cause organisms in the gut to migrate to the bloodstream, frequently resulting in bacterial infection. Michael Ellis and colleagues from the United Arab Emirates investigated whether interleukin 11 (IL-11)-an agent involved in the immune response and thought to protect gastrointestinal cells from toxicity associated with chemotherapy-could prevent gut-associated infections.

40 patients with blood cancer received either 50 microgrammes per kg bodyweight of IL-11 or placebo as daily injections. Significantly fewer patients who received IL-11 rather than placebo developed bacterial infection, particularly of gastrointestinal origin. IL-11 slowed the time to first infection compared with placebo


Michael Ellis comments: “The administration of IL-11 reduces bacteraemia, predominantly of gastrointestinal origin, in patients with haemological malignant disease undergoing chemotherapy…the number of patients enrolled was small, so larger clinical trials should be done to confirm our findings. If our findings are substantiated, IL-11 could offer a new non-antibiotic approach to the management of sepsis in these patients.”

Contact: Dr Michael E Ellis, Department of Medicine, Faculty of Medicine and Health Sciences, PO Box 17666, Al Ain, United Arab Emirates; T) +971 3722 3942; E) michael.ellis@uaeu.ac.ae

Richard Lane | alfa
Further information:
http://www.alphagalileo.org/nontextfiles/P_5258_12354_1.pdf

More articles from Health and Medicine:

nachricht New vaccine production could improve flu shot accuracy
25.07.2017 | Duke University

nachricht Chances to treat childhood dementia
24.07.2017 | Julius-Maximilians-Universität Würzburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA mission surfs through waves in space to understand space weather

25.07.2017 | Physics and Astronomy

Strength of tectonic plates may explain shape of the Tibetan Plateau, study finds

25.07.2017 | Earth Sciences

The dense vessel network regulates formation of thrombocytes in the bone marrow

25.07.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>