Diabetes is a chronic metabolic disorder that afflicts 17 million people in the United States and is the fourth leading cause of death. Over 2 million patients suffer from its most severe form - childhood diabetes – also known as Type 1, juvenile or insulin-dependent diabetes. We now understand that childhood diabetes is an autoimmune illness, where the bodys own white blood cells, which normally fight infection, turn and act against the body. These white blood cells target a specific group of cells in the pancreas – beta cells – that produce insulin, the hormone necessary to convert food into energy. Over time, such a large number of beta cells are destroyed that there is a lack of insulin and diabetes develops.
Scientists have long sought a means to predict the onset of diabetes through routine blood tests of destructive white blood cells so that high-risk individuals could be treated before all their beta cells are destroyed and they become diabetic. Progress has been so limited however, that it has been debated whether these cells were present in the blood at levels high enough to facilitate direct detection.
In the January 15 issue of the Journal of Clinical Investigation, Rusung Tan and colleagues at British Columbias Childrens Hospital, Canada, reveal a method for directly measuring the level of these self-destructive cells in the blood of mice and demonstrate that these levels reliably distinguish mice that go on to develop diabetes from those that do not.
'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS
New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).
Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
16.02.2018 | Information Technology
16.02.2018 | Health and Medicine
16.02.2018 | Physics and Astronomy