Diabetes is a chronic metabolic disorder that afflicts 17 million people in the United States and is the fourth leading cause of death. Over 2 million patients suffer from its most severe form - childhood diabetes – also known as Type 1, juvenile or insulin-dependent diabetes. We now understand that childhood diabetes is an autoimmune illness, where the bodys own white blood cells, which normally fight infection, turn and act against the body. These white blood cells target a specific group of cells in the pancreas – beta cells – that produce insulin, the hormone necessary to convert food into energy. Over time, such a large number of beta cells are destroyed that there is a lack of insulin and diabetes develops.
Scientists have long sought a means to predict the onset of diabetes through routine blood tests of destructive white blood cells so that high-risk individuals could be treated before all their beta cells are destroyed and they become diabetic. Progress has been so limited however, that it has been debated whether these cells were present in the blood at levels high enough to facilitate direct detection.
In the January 15 issue of the Journal of Clinical Investigation, Rusung Tan and colleagues at British Columbias Childrens Hospital, Canada, reveal a method for directly measuring the level of these self-destructive cells in the blood of mice and demonstrate that these levels reliably distinguish mice that go on to develop diabetes from those that do not.
Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy