Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Frequency of light-to-moderate drinking reduces heart disease risk in men

09.01.2003


A 12-year study of 38,077 male health professionals found that men who drank alcohol three or more days per week had a reduced risk of heart attack compared with men who drank less frequently. Men who drank less than one drink a day had similar risk reduction to those who drank three.



Many epidemiologic studies have reported that moderate drinking--for men two drinks a day--is associated with a reduced risk of heart disease. This study looked at the relationship between quantity and frequency and found that it was the frequency of drinking--not the amount, the type of alcohol, or whether or not it was consumed with a meal--that was the key factor in lowered heart disease risk. Compared with men who drank less than once a week, men who consumed alcohol three or four days a week had approximately 2/3 (68 percent) the risk of heart attack, and men who consumed alcohol five to seven days per week had slightly less (63 percent) the risk. Study data suggested no additional cardiac benefit to drinking more than 2 drinks a day. Also, the study authors point out that the small number of study participants who drank roughly three and a half or more drinks (50 or more grams of alcohol) per day limited their ability to study the harmful effects of heavy drinking. However, heavy drinking has well documented adverse health effects.

The study, published in this week’s New England Journal of Medicine, was based on an analysis of data from the Health Professionals Follow-up Study, which has followed a population of male dentists, veterinarians, optometrists, osteopathic physicians, and podiatrists, ages 40 to 75, for 12 years. Kenneth J. Mukamal, M.D., M.P.H., at Beth Israel Deaconess Medical Center, was lead author for the project, which included scientists from the University of Sydney, Sydney, Australia; the Harvard School of Public Health, Boston; Brigham and Women’s Hospital, Harvard Medical School, Boston; and the Massachusetts General Hospital, Boston. The National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Heart, Lung, and Blood Institute (NHLBI), and the National Cancer Institute, all components of the federal government’s National Institutes of Health, supported the study.


NIAAA director Ting-Kai Li, M.D., said, "This rigorously conducted observational study adds to the epidemiologic evidence of a strong association between light-to-moderate alcohol consumption and reduced risk of heart disease. Only by research on the mechanisms of alcohol’s effects on the cardiovascular system, and perhaps the liver, and the genetic background of how individuals respond to alcohol, will we provide a scientifically informed means for assessing the risks and benefits of alcohol use on a person-to-person basis."

NHLBI director Claude Lenfant, M.D., said, "There are well-proven ways to prevent cardiovascular disease and reduce its risks, including lowering cholesterol levels and blood pressure, maintaining a healthy weight, being physically active, and stopping smoking. These preventive measures do not have the risks associated with alcohol consumption. Therefore, we do not advise the public to begin drinking alcohol to prevent heart disease. However, those who already drink alcohol should be aware that current evidence suggests that moderate drinking may reduce the risk of heart disease in some individuals."

At entry into this study, all participants had to be free of heart disease. Participants in the study completed questionnaires on diet every four years. Investigators confirmed the validity of the questionnaire responses by comparing them with seven-day dietary records in 127 participants. The investigators controlled for numerous health and dietary factors, including smoking, exercise, diet, and family history of premature heart attack. Also, because alcohol use changes over time, and the effects of alcohol may be short-term, the study tracked the effect of recent versus baseline alcohol consumption, and found that the level of risk was more strongly related to recent, rather than past, consumption.

By the end of the 12-year follow-up, the investigators had documented 1,418 heart attacks. Men who consumed alcohol three or more times a week had a reduced risk of fatal or nonfatal heart attack, even when the amount consumed was only 10 grams of alcohol a day or less. A standard drink--a 12-ounce bottle of beer, a 5-ounce glass of wine, or 1.5 ounces of 80-proof distilled spirits--has between 11 and 14 grams of alcohol. Dr. Mukamal, the study’s lead author, said, "We found little difference among different alcoholic beverage types in our study. This further emphasizes the role of frequent intake, rather than any specific beverage type, in the link between moderate drinking and heart attack risk."

In an accompanying editorial, Ira J. Goldberg, M.D., of the Columbia University College of Physicians and Surgeons, New York, points out that some studies show a reduction in cardiovascular disease, but not overall mortality, in patients who drink alcoholic beverages (this study did not report on overall mortality). He notes that alcohol has toxic effects that are well established and that additional research is needed to inform physicians on how to advise their patients.


For interviews with Dr. Mukamal, please contact Bonnie Prescott at the Beth Israel Deaconess Medical Center, 617-667-7306. For interviews with Dr. Li, please call the NIAAA press office at 301-443-3860. For interviews with NHLBI scientists, please call the NHLBI communications office at 301-496-4236.

The paper, "Roles of Drinking Pattern and Type of Alcohol Consumed in Coronary Heart Disease in Men," appears in the January 9, 2003 issue of The New England Journal of Medicine 348(2):109-118. An accompanying editorial appears on pages 163-164.

The Dietary Guidelines for Americans, issued jointly by the U.S. Department of Agriculture and the U.S. Department of Health and Human Services, defines moderate drinking for men as no more than 2 drinks per day. The Guidelines can be viewed on-line at the website www.nutrition.gov.

The National Institutes of Health (NIH) is the Federal Government’s primary agency for biomedical and behavioral research. NIH is a component of the U.S. Department of Health and Human Services.


Ann Bradley | EurekAlert!
Further information:
http://www.niaaa.nih.gov/

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

Bodyguards in the gut have a chemical weapon

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>