Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Miniature implantable sensor likely lifesaver for patients

25.11.2002


Using a tiny wireless sensor developed at Oak Ridge National Laboratory, doctors will know in minutes instead of hours if an organ is getting adequate blood flow after transplant or reconstructive surgery.



Conventional methods for assessing circulation involve invasive procedures or extensive laboratory testing. In some cases, by the time doctors realize there isn’t adequate blood flow to an organ or tissue, irreversible damage already has occurred.

"Our goal is to offer a technique that provides the physician with a very early indication of whether the surgery is successful," said Nance Ericson, who leads the effort from ORNL’s Engineering Science and Technology Division. Ericson is working with Mark Wilson, a surgeon at the University of Pittsburgh, and Gerard Coté of Texas A&M University.


The tiny implantable sensor – about the diameter of a quarter -- and micro-instrumentation being developed by Ericson would provide real-time information by transmitting data to a nearby receiver. Specifically, the unit employs optical sensors to assess tissue circulation. Preliminary tests using laboratory rats have provided encouraging results.

"Although we have more work to do, we are extremely optimistic that this technology will dramatically improve the ability of physicians to care for critically ill patients," Wilson said.

While Wilson provides the practicing medical component required in this research, Coté, who heads the optical biosensing laboratory within the Department of Biomedical Engineering at Texas A&M, provides expertise in modeling, post-processing and sensor optimization. Ericson and ORNL colleagues bring to the team vast knowledge in engineering, signal processing, system design, radio frequency telemetry design, and fabrication and micro-fabrication techniques.

Over the next year, Ericson will be working to miniaturize the sensors and associated electronics, which will enable surgeons to implant the sensor in the precise area of interest, either as a subdermal or deep-tissue implant. Ericson envisions the sensor remaining in the body, which would avoid additional surgery; however, that is an area that may require additional evaluation. Other efforts include biosensor optimization, design of low-power highly miniaturized signal processing and telemetry electronics, and development of encapsulation techniques.

Once they have made sufficient progress in these areas, the research team plans to conduct additional testing of the sensing techniques to demonstrate clinical significance. Finally, the procedure would be subject to clinical trials and Food and Drug Administration approval.

Assuming the technology passes all the tests, Ericson envisions this work leading to significant benefits.

"This research is based on several key developments in optics and micro-fabrication that have far-reaching implications for future directions in a multitude of clinically significant biomedical sensing systems," Ericson said. "Through these innovations, biomedical microsensors are poised to make major technology advances to help meet the critical needs of patients in hospitals, emergency care facilities and extended-care facilities."

The ability to prevent -- or at least detect -- circulation problems quickly could lead not only to fewer complications during surgery, but also could reduce the number of deaths attributable to those complications.

Although not a part of this project, Ericson sees this leading to several other photonics-based microsensors for making measurements in a number of areas. For example, this approach could be useful for measuring arterial blood gases, which are primary indicators of respiratory function, or serum lactate, which is a marker for the severity of tissue injury. Current methods require obtaining blood samples and then sending those samples to a lab for analysis.


Funding for this research is provided by DOE’s Office of Science. Initial funding began in 1997 through ORNL’s Laboratory Directed Research and Development program, also funded by DOE.

ORNL is a DOE multiprogram research facility managed by UT-Battelle.

Ron Walli | EurekAlert!
Further information:
http://www.ornl.gov/news

More articles from Health and Medicine:

nachricht New leukemia treatment offers hope
23.09.2016 | King Abdullah University of Science and Technology

nachricht Alzheimer’s: Cellular Mechanism Provides Explanation Model for Declining Memory Performance
21.09.2016 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: OLED microdisplays in data glasses for improved human-machine interaction

The Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP has been developing various applications for OLED microdisplays based on organic semiconductors. By integrating the capabilities of an image sensor directly into the microdisplay, eye movements can be recorded by the smart glasses and utilized for guidance and control functions, as one example. The new design will be debuted at Augmented World Expo Europe (AWE) in Berlin at Booth B25, October 18th – 19th.

“Augmented-reality” and “wearables” have become terms we encounter almost daily. Both can make daily life a little simpler and provide valuable assistance for...

Im Focus: Artificial Intelligence Helps in the Discovery of New Materials

With the help of artificial intelligence, chemists from the University of Basel in Switzerland have computed the characteristics of about two million crystals made up of four chemical elements. The researchers were able to identify 90 previously unknown thermodynamically stable crystals that can be regarded as new materials. They report on their findings in the scientific journal Physical Review Letters.

Elpasolite is a glassy, transparent, shiny and soft mineral with a cubic crystal structure. First discovered in El Paso County (Colorado, USA), it can also be...

Im Focus: Complex hardmetal tools out of the 3D printer

For the first time, Fraunhofer IKTS shows additively manufactured hardmetal tools at WorldPM 2016 in Hamburg. Mechanical, chemical as well as a high heat resistance and extreme hardness are required from tools that are used in mechanical and automotive engineering or in plastics and building materials industry. Researchers at the Fraunhofer Institute for Ceramic Technologies and Systems IKTS in Dresden managed the production of complex hardmetal tools via 3D printing in a quality that are in no way inferior to conventionally produced high-performance tools.

Fraunhofer IKTS counts decades of proven expertise in the development of hardmetals. To date, reliable cutting, drilling, pressing and stamping tools made of...

Im Focus: Launch of New Industry Working Group for Process Control in Laser Material Processing

At AKL’16, the International Laser Technology Congress held in May this year, interest in the topic of process control was greater than expected. Appropriately, the event was also used to launch the Industry Working Group for Process Control in Laser Material Processing. The group provides a forum for representatives from industry and research to initiate pre-competitive projects and discuss issues such as standards, potential cost savings and feasibility.

In the age of industry 4.0, laser technology is firmly established within manufacturing. A wide variety of laser techniques – from USP ablation and additive...

Im Focus: New laser joining technologies at ‘K 2016’ trade fair

Every three years, the plastics industry gathers at K, the international trade fair for plastics and rubber in Düsseldorf. The Fraunhofer Institute for Laser Technology ILT will also be attending again and presenting many innovative technologies, such as for joining plastics and metals using ultrashort pulse lasers. From October 19 to 26, you can find the Fraunhofer ILT at the joint Fraunhofer booth SC01 in Hall 7.

K is the world’s largest trade fair for the plastics and rubber industry. As in previous years, the organizers are expecting 3,000 exhibitors and more than...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Experts from industry and academia discuss the future mobile telecommunications standard 5G

23.09.2016 | Event News

ICPE in Graz for the seventh time

20.09.2016 | Event News

Using mathematical models to understand our brain

16.09.2016 | Event News

 
Latest News

Chains of nanogold – forged with atomic precision

23.09.2016 | Life Sciences

New leukemia treatment offers hope

23.09.2016 | Health and Medicine

Self-assembled nanostructures hit their target

23.09.2016 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>