Scientists at the University of Pennsylvania School of Veterinary Medicine have successfully transplanted specialized cells that are critical to sperm development in mice, restoring sperm production in once-infertile animals.
The research, reported on the Web site of the journal Biology of Reproduction, may give scientists a better understanding of how Sertoli cells -- which surround spermatogenic stem cells -- nourish sperm production and the survival of stem cells.
"Spermatogenesis is a highly organized process, requiring just the right environment, or ’niche,’ around the germ line stem cells," said Ralph L. Brinster, professor of reproductive physiology at Penn. "The Sertoli cells are essential to this environment, and it appears that by replacing them, we can essentially reconstruct the niche in which sperm development takes place."
Steve Bradt | EurekAlert!
Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
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