Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Physicians offer new solution for blood transfusions

12.11.2002


The successful transfusion of a cell-free blood product on a 14-year-old Jehovah’s Witness may offer a solution for patients opposed to blood transfusions due to religious or personal beliefs.



"This was the first successful use of a human cell-free hemoglobin solution in a pediatric patient to manage life-threatening anemia due to an autoimmune disease," says Dr. Brian Kavanagh, professor of medicine at the University of Toronto and staff physician in critical care medicine at The Hospital for Sick Children. The patient suffered from immune thrombocytopenia, a condition that attacks platelets in the body. Platelets are present in blood and help blood clot; if platelet counts are very low, minor injuries or trauma can become very serious if the patient continues to bleed.

Kavanagh and colleagues Drs. Johann Hitzler and Natalie Anton treated the patient last year after she entered the hospital’s emergency room for a nosebleed that did not stop. Instead of a blood transfusion, they used a biochemically manufactured solution that contains hemoglobin but does not contain red blood cells. The solution has been used in adults but never for a child in this kind of situation, Kavanagh says.


While more study needs to be done with pediatric patients, Kavanagh says this cell-free hemoglobin is a viable alternative for Jehovah’s Witnesses. "Most current blood replacement options are fluids, plasma and other types of liquids that provide volume for blood but don’t provide the oxygen-carrying capacity. This solution provides oxygen-carrying capacity in exactly the same way that blood cells in hemoglobin do. That’s the crux of the matter. Still, only careful study will fully determine the balance of benefits and risk."

Kavanagh and colleagues reported this case in a fall issue of the British Journal of Haematology.


CONTACT: Dr. Brian Kavanagh of medicine at U of T and The Hospital for Sick Children, 416-813-6860, brian.kavanagh@sickkids.ca
or Janet Wong, U of T public affairs, 416-978-5949, jf.wong@utoronto.ca


Janet Wong | EurekAlert!
Further information:
http://www.utoronto.ca/

More articles from Health and Medicine:

nachricht Electrical 'switch' in brain's capillary network monitors activity and controls blood flow
27.03.2017 | Larner College of Medicine at the University of Vermont

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Northern oceans pumped CO2 into the atmosphere

27.03.2017 | Earth Sciences

Fingerprint' technique spots frog populations at risk from pollution

27.03.2017 | Life Sciences

Big data approach to predict protein structure

27.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>