Will allow non-invasive study of neurochemistry, behavior, and disease progression
Scientists at the U.S. Department of Energys Brookhaven National Laboratory have demonstrated that a miniature positron emission tomography (PET) scanner, known as microPET, and the chemical markers used in traditional PET scanning are sensitive enough to pick up subtle differences in neurochemistry between known genetic variants of mice.
This "proof-of-principle" experiment, described in the November issue of the Journal of Nuclear Medicine, "opens up a whole new, non-invasive way to study and follow transgenic or genetically engineered strains of mice that serve as animal models for human neurological diseases, such as Parkinsons and Alzheimers disease or psychiatric diseases such as substance abuse, depression, and anxiety disorders," said Panayotis (Peter) Thanos, lead author of the paper. Studying animal models may help scientists better understand and develop treatments for the human diseases.
Karen McNulty Walsh | EurekAlert!
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