Secretin is active in a brain region implicated in autism
Researchers from the Brain Imaging Center at McLean Hospital and Repligen Corporation (Nasdaq: RGEN) reported today the results of a clinical trial designed to assess the neurological activity of secretin by functional magnetic resonance imaging (fMRI). The results demonstrate for the first time in humans, that secretin is active in the central nervous system and that it potentiates activity in the amygdala, a region of the brain involved in social integration and implicated in autism. The findings were presented today by Deborah Yurgelun-Todd, Ph.D., of McLean Hospital, the studys Principal Investigator, at the International Meeting for Autism Research, a satellite meeting of the Society for Neuroscience.
"Our results demonstrate for the first time that secretin is a neuroactive peptide in humans and that it acts on a brain region known to be important for social interaction," stated Yurgelun-Todd, Director of Cognitive Neuroimaging at the Brain Imaging Center at McLean Hospital. "These findings suggest that secretin may have a role in modulating certain social behavior in humans."
Renee L. Connolly | EurekAlert!
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