A project which aims to make laboratory-grown leukaemia cells change form and then be used to prime a patient’s own immune system to kill off malignant cells has begun in Edinburgh. If successful, the study could give clinicians a way of destroying residual leukaemic cells which are undetectable by microscope. The findings could be helpful in the treatment of acute myeloblastic leukaemia (AML), one of the most common forms of leukaemia in adults.
Although about 70% of patients with AML achieve complete remission of the disease after chemotherapy treatment, around half of the younger patients and the majority of elderly patients will ultimately relapse and die as a consequence of the disease. Three years survival rates are about 40% in younger patients and 10% in older patients.
This study, based at the John Hughes Bennett Laboratories at the University of Edinburgh, is led by haematologist Dr Marc Turner, who is Clinical Director of the Edinburgh and SE Scotland Blood Transfusion Centre.Dr Turner explained: “Relapse after initial successful chemotherapy is caused by residual leukaemic cells which are below a level which can be detected by microscope. Sometimes, they can cause the disease to restart, and it is much harder to treat the second time around. Methods of eliminating this minimal residual disease, such as bone marrow transplantation, can be successful but this form of treatment is only suitable for younger patients who are able to withstand the side effects of the treatment.”
Linda Menzies | alfa
Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena
Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University
A study carried out by an international team of researchers and published in the journal Physical Review X shows that ion-trap technologies available today are suitable for building large-scale quantum computers. The scientists introduce trapped-ion quantum error correction protocols that detect and correct processing errors.
In order to reach their full potential, today’s quantum computer prototypes have to meet specific criteria: First, they have to be made bigger, which means...
Since 2016, German and Spanish researchers, among them scientists from the University of Göttingen, have been hunting for exoplanets with the “Carmenes”...
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
18.12.2017 | Life Sciences
18.12.2017 | Materials Sciences
18.12.2017 | Life Sciences