Findings are cover story of Oct. 15 issue of Cancer Research
Researchers at Cedars-Sinai Medical Centers Maxine Dunitz Neurosurgical Institute have successfully tested a new treatment for brain cancer by utilizing neural stem cells to track and destroy cancer cells within the brain. Scientists hope the encouraging results may eventually lead to an effective treatment for glioma, the most aggressive form of primary brain tumor in humans. The study, conducted in mice with experimental brain cancer, is featured on the cover of the Oct. 15 issue of the journal Cancer Research.
The prognosis has historically been extremely poor for patients diagnosed with malignant gliomas. These tumors have very poorly defined margins, and glioma cells often spread deep into healthy brain tissue making their effective surgical removal extremely difficult. Often, pockets of tumor cells break off from the main tumor and migrate deep into non-tumorous areas of the brain. Therefore, even if the original tumor is completely removed or destroyed, the risk of recurrence is high as cells in these distant "satellites" multiply and eventually re-form a new brain tumor. Due to these characteristics, treating brain cancer has been extremely difficult.
Sandra Van | EurekAlert!
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