Changes in the brains white matter may play a major role in the onset of Alzheimers disease, whose baffling origin has traditionally been blamed on the gray matter. The new findings could provide a fresh direction for Alzheimers research in this neglected part of the brain, offering the potential for early diagnosis and enhanced therapies.
The results are reported in the Sept. 17 print edition of Biochemistry, a peer-reviewed journal of the American Chemical Society, the worlds largest scientific society.
"Alzheimers disease is conventionally considered a disease of the brain gray matter because its most prominent consequence is severe memory loss," says Alex Roher, M.D., Ph.D., director of the Sun Health Research Institute in Sun City, Ariz., and lead author of the paper. The overwhelming majority of Alzheimers research has focused on gray matter, despite the fact that white matter makes up about 50 percent of total brain tissue and is substantially altered during Alzheimers progression, Roher says.
Beverly Hassell | EurekAlert!
Finnish research group discovers a new immune system regulator
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A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
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23.02.2018 | Physics and Astronomy