Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Multiple pets may decrease children’s allergy risk

28.08.2002


Children raised in a house with two or more dogs or cats during the first year of life may be less likely to develop allergic diseases as compared with children raised without pets, according to a study in the August 28 issue of the Journal of the American Medical Association. The study was supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Environmental Health Sciences (NIEHS).



"The striking finding here is that high pet exposure early in life appears to protect against not only pet allergy but also other types of common allergies, such as allergy to dust mites, ragweed, and grass," says Marshall Plaut, M.D., chief of the allergic mechanisms section at NIAID. "Other studies have suggested a protective effect of pet exposure on allergy and asthma symptoms, but generally have looked only at whether pet exposure reduced pet allergy. This new finding changes the way scientists think about pet exposure; scientists must now figure out how pet exposure causes a general shift of the immune system away from an allergic response."

In their paper, lead author Dennis R. Ownby, M.D., of the Medical College of Georgia, and colleagues suggest that bacteria carried by pets may be responsible for suppressing the immune system’s allergic response. These bacteria release molecules called endotoxins, and endotoxins are believed to shift the developing immune system away from responding to allergens through a class of lymphocytes called Th-2 cells, which are associated with allergic reactions. Instead, endotoxins may stimulate the immune system to activate Th-1 cells, which may block allergic reactions.


The researchers followed 474 children from birth to six or seven years of age. When the children were one year old, the researchers contacted parents by telephone to find out how many pets were in the home. When the children were two years old, researchers measured the level of dust mite allergen in their bedrooms. When the children were six or seven, the researchers tested them for allergic antibodies to common allergens by two approaches - a skin prick test and a blood measurement.

After adjusting for factors such as dust mite allergen levels, parental smoking, and current dog or cat ownership, the researchers found that children exposed to two or more dogs or cats during the first year of life were on average 66 to 77 percent less likely to have any allergic antibodies to common allergens, as compared with children exposed to only one or no pets during their first year.

"Our findings suggest an area of research with many possibilities, one that could potentially bear fruit over the next decade or so," says Dr. Ownby. "If we could find out exactly what it is about pets or the bacteria they carry that prevents the allergic response, scientists might be able to develop a new allergy therapy based on that knowledge."

Gregory Roa | EurekAlert!
Further information:
http://www.niaid.nih.gov/

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>